Literature DB >> 14748606

Total synthesis of aigialomycin D.

Xudong Geng1, Samuel J Danishefsky.   

Abstract

[reaction: see text] The first total synthesis of resorcinylic macrolide aigialomycin D was described. The resorcinylic moiety was constructed by a highly efficient Diels-Alder reaction using a disiloxydiene and a 14-membered "ynolide" as the dienophile synthesized by ring-forming olefin metathesis.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14748606     DOI： 10.1021/ol036258m

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Total synthesis of LL-Z1640-2 utilizing a late-stage intramolecular Nozaki-Hiyama-Kishi reaction.

Authors:  Christopher A Leclair; Matthew B Boxer; Craig J Thomas; David J Maloney
Journal:  Tetrahedron Lett       Date:  2010-12-29       Impact factor: 2.415

2.  Exploring aigialomycin d and its analogues as protein kinase inhibitors for cancer targets.

Authors:  Jin Xu; Anqi Chen; Mei-Lin Go; Kassoum Nacro; Boping Liu; Christina L L Chai
Journal:  ACS Med Chem Lett       Date:  2011-07-17       Impact factor: 4.345

Review 3.  Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides.

Authors:  Jing Xu; Cheng-shi Jiang; Zai-long Zhang; Wen-quan Ma; Yue-wei Guo
Journal:  Acta Pharmacol Sin       Date:  2014-01-27       Impact factor: 6.150

Review 4.  The current status of natural products from marine fungi and their potential as anti-infective agents.

Authors:  Punyasloke Bhadury; Balsam T Mohammad; Phillip C Wright
Journal:  J Ind Microbiol Biotechnol       Date:  2006-01-21       Impact factor: 4.258

5.  Diels-Alder construction of regiodifferentiated meta-amino phenols and derivatives.

Authors:  Marisa G Weaver; Wen-Ju Bai; Stephen K Jackson; Thomas R R Pettus
Journal:  Org Lett       Date:  2014-02-13       Impact factor: 6.005
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.