Literature DB >> 14745077

Association between tumor necrosis factor-alpha promoter polymorphism and Alzheimer's disease.

Suk Ling Ma1, Nelson L S Tang, Linda C W Lam, Helen F K Chiu.   

Abstract

Tumor necrosis factor-alpha (TNFalpha) gene polymorphisms have been reported to be associated with Alzheimer's disease (AD) in Caucasian populations. Three TNFalpha polymorphisms (-857, -863, and -1,031) were studied in a Chinese population. A high-risk TNFalpha haplotype (-1,031C-863C-857C) with an odds ratio of 2.54 (95% CI 1.37 to 4.79) for AD was identified. No interaction effect of APOE and TNFalpha genotypes was found, but both acted as important risk factors for AD.

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Year:  2004        PMID： 14745077     DOI： 10.1212/01.wnl.0000103288.49441.e4

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  14 in total

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Review 2.  Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system.

Authors:  Sara L Montgomery; William J Bowers
Journal:  J Neuroimmune Pharmacol       Date:  2011-07-05       Impact factor: 4.147

3.  Association of polymorphism of tumor necrosis factor-alpha gene promoter region with outcome of hepatitis B virus infection.

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Journal:  World J Gastroenterol       Date:  2005-09-07       Impact factor: 5.742

4.  Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology.

Authors:  Fiona E McAlpine; Jae-Kyung Lee; Ashley S Harms; Kelly A Ruhn; Mathew Blurton-Jones; John Hong; Pritam Das; Todd E Golde; Frank M LaFerla; Salvatore Oddo; Armin Blesch; Malú G Tansey
Journal:  Neurobiol Dis       Date:  2009-04       Impact factor: 5.996

Review 5.  The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?

Authors:  Kevin R Doty; Marie-Victoire Guillot-Sestier; Terrence Town
Journal:  Brain Res       Date:  2014-09-08       Impact factor: 3.252

6.  Cluster analysis of risk factor genetic polymorphisms in Alzheimer's disease.

Authors:  C N Randall; D Strasburger; J Prozonic; S N Morris; A D Winkie; G R Parker; D Cheng; E M Fennell; I Lanham; N Vakil; J Huang; H Cathcart; R Huang; S E Poduslo
Journal:  Neurochem Res       Date:  2008-02-29       Impact factor: 3.996

7.  Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer's disease.

Authors:  Fiona E McAlpine; Malú G Tansey
Journal:  J Inflamm Res       Date:  2008-11-06

8.  Genetics of late-onset Alzheimer's disease: update from the alzgene database and analysis of shared pathways.

Authors:  Paolo Olgiati; Antonis M Politis; George N Papadimitriou; Diana De Ronchi; Alessandro Serretti
Journal:  Int J Alzheimers Dis       Date:  2011-12-10

9.  Polymorphism in the TNF-α(-863) locus associated with reduced risk of primary open angle glaucoma.

Authors:  Chun-Yuan Wang; Ying-Cheng Shen; Li-Chen Wei; Keng-Hung Lin; Shih-Chao Feng; Yi-Yin Yang; Chun-Hung Chiu; Hin-Yeung Tsai
Journal:  Mol Vis       Date:  2012-03-31       Impact factor: 2.367

10.  Panel of Genetic Variations as a Potential Non-invasive Biomarker for Early Diagnosis of Alzheimer's Disease.

Authors:  Suk Ling Ma; Linda Chiu Wa Lam
Journal:  Clin Psychopharmacol Neurosci       Date:  2011-08-31       Impact factor: 2.582
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