Literature DB >> 14744164

Impact of age at onset and duration of illness on the expression of comorbidities in obsessive-compulsive disorder.

Juliana B Diniz1, Maria C Rosario-Campos, Roseli G Shavitt, Mariana Curi, Ana G Hounie, Sergio A Brotto, Euripedes C Miguel.   

Abstract

BACKGROUND: Obsessive-compulsive disorder (OCD) patients usually experience comorbidities including tics, trichotillomania, body dysmorphic disorder, and mood and anxiety disorders. The present report verifies how age at onset of obsessive-compulsive symptoms and duration of illness are associated with comorbid diagnoses in OCD patients.
METHOD: Psychiatric comorbidity was assessed using a structured clinical interview in 161 consecutive outpatients referred for treatment between 1996 and 2001 who met DSM-IV criteria for OCD. Age at onset and duration of illness were retrospectively assessed by direct interviews.
RESULTS: An earlier age at onset of obsessive-compulsive symptoms was associated with tic disorders, while longer illness duration was associated with depressive disorder (major depressive disorder or dysthymia) and social phobia.
CONCLUSION: Age at onset and duration of OCD illness are meaningful variables affecting the expression of comorbidities in OCD. Tic disorders and OCD may share common etiologic pathways. Depressive disorders, in contrast, may be secondary complications of OCD.

Entities:  

Mesh:

Year:  2004        PMID: 14744164     DOI: 10.4088/jcp.v65n0104

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  15 in total

Review 1.  Should an obsessive-compulsive spectrum grouping of disorders be included in DSM-V?

Authors:  Katharine A Phillips; Dan J Stein; Scott L Rauch; Eric Hollander; Brian A Fallon; Arthur Barsky; Naomi Fineberg; David Mataix-Cols; Ygor Arzeno Ferrão; Sanjaya Saxena; Sabine Wilhelm; Megan M Kelly; Lee Anna Clark; Anthony Pinto; O Joseph Bienvenu; Joanne Farrow; James Leckman
Journal:  Depress Anxiety       Date:  2010-06       Impact factor: 6.505

2.  Comment on Tükel et al., "The clinical impact of mood disorder comorbidity on obsessive-compulsive disorder" (Eur Arch Psychiatry Clin Neurosci, 256(4):240-245).

Authors:  Juliana Belo Diniz; Cilly Klüger Issler; Beny Lafer; Euripedes Constantino Miguel
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2006-12-05       Impact factor: 5.270

3.  Differential Parental Influence in the Familial Aggregation of Obsessive Compulsive Disorder.

Authors:  Caleb M Pardue; Nicholas J Sibrava; Christina L Boisseau; Maria C Mancebo; Jane L Eisen; Steven A Rasmussen
Journal:  J Obsessive Compuls Relat Disord       Date:  2014-07-01       Impact factor: 1.677

4.  Longitudinal course of obsessive-compulsive disorder in patients with anxiety disorders: a 15-year prospective follow-up study.

Authors:  Brook A Marcks; Risa B Weisberg; Ingrid Dyck; Martin B Keller
Journal:  Compr Psychiatry       Date:  2011-02-23       Impact factor: 3.735

5.  Clinical and cognitive correlates of depressive symptoms among youth with obsessive compulsive disorder.

Authors:  Tara S Peris; R Lindsey Bergman; Joan R Asarnow; Audra Langley; James T McCracken; John Piacentini
Journal:  J Clin Child Adolesc Psychol       Date:  2010

6.  Impact of Gender, Age at Onset, and Lifetime Tic Disorders on the Clinical Presentation and Comorbidity Pattern of Obsessive-Compulsive Disorder in Children and Adolescents.

Authors:  Canan Tanidir; Hilal Adaletli; Hatice Gunes; Ali Guven Kilicoglu; Caner Mutlu; Mustafa Kayhan Bahali; Tugce Aytemiz; Ozden Sukran Uneri
Journal:  J Child Adolesc Psychopharmacol       Date:  2015-06       Impact factor: 2.576

7.  Substance use disorders in an obsessive compulsive disorder clinical sample.

Authors:  Maria C Mancebo; Jon E Grant; Anthony Pinto; Jane L Eisen; Steven A Rasmussen
Journal:  J Anxiety Disord       Date:  2008-09-06

Review 8.  Genetic and environmental influences on obsessive-compulsive disorder.

Authors:  Jessica R Grisham; Tracy M Anderson; Perminder S Sachdev
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2008-03       Impact factor: 5.270

9.  Juvenile-onset OCD: clinical features in children, adolescents and adults.

Authors:  M C Mancebo; A M Garcia; A Pinto; J B Freeman; A Przeworski; R Stout; J S Kane; J L Eisen; S A Rasmussen
Journal:  Acta Psychiatr Scand       Date:  2008-08       Impact factor: 6.392

10.  The relationship between tics, OC, ADHD and autism symptoms: A cross- disorder symptom analysis in Gilles de la Tourette syndrome patients and family-members.

Authors:  Hilde M Huisman-van Dijk; Rens van de Schoot; Marleen M Rijkeboer; Carol A Mathews; Daniëlle C Cath
Journal:  Psychiatry Res       Date:  2016-01-22       Impact factor: 3.222

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