Literature DB >> 14743842

Management and prevention strategies for respiratory syncytial virus (RSV) bronchiolitis in infants and young children: a review of evidence-based practice interventions.

Allison C Cooper1, Nancy Cantey Banasiak, Patricia Jackson Allen.   

Abstract

Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and pneumonia among infants and children. The purpose of this paper is to review the epidemiology, etiology, pathophysiology, clinical manifestations, risk factors, and assessment of RSV infection in infants and young children. There is a lack of consensus regarding the optimal treatment for children with RSV infection. Bronchodilators, racemic epinephrine, inhaled and systemic corticosteroids, RSV-immunoglobulin (RSV-IG), and ribavirin have all been used for treatment of children with RSV infection. A review of current research indicates supportive and symptomatic management should be the mainstay of treatment. Ultimately, prevention of infection through education and immunotherapy is the key to reducing the morbidity and mortality associated with RSV bronchiolitis.

Entities:  

Mesh:

Year:  2003        PMID: 14743842

Source DB:  PubMed          Journal:  Pediatr Nurs        ISSN: 0097-9805


  12 in total

Review 1.  Evidence based treatment of bronchiolitis.

Authors:  G R Sethi; Gaurav Nagar
Journal:  Indian J Pediatr       Date:  2004-08       Impact factor: 1.967

Review 2.  Respiratory syncytial virus bronchiolitis.

Authors:  Alexander K C Leung; James D Kellner; H Dele Davies
Journal:  J Natl Med Assoc       Date:  2005-12       Impact factor: 1.798

3.  Controversies' clarification regarding ribavirin efficacy in measles and coronaviruses: Comprehensive therapeutic approach strictly tailored to COVID-19 disease stages.

Authors:  George D Liatsos
Journal:  World J Clin Cases       Date:  2021-07-06       Impact factor: 1.337

4.  The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase.

Authors:  Pieter Leyssen; Jan Balzarini; Erik De Clercq; Johan Neyts
Journal:  J Virol       Date:  2005-02       Impact factor: 5.103

Review 5.  Mechanisms of action of ribavirin against distinct viruses.

Authors:  Jason D Graci; Craig E Cameron
Journal:  Rev Med Virol       Date:  2006 Jan-Feb       Impact factor: 6.989

Review 6.  Ribavirin: a drug active against many viruses with multiple effects on virus replication and propagation. Molecular basis of ribavirin resistance.

Authors:  Stéphanie Beaucourt; Marco Vignuzzi
Journal:  Curr Opin Virol       Date:  2014-05-19       Impact factor: 7.090

Review 7.  Peptides to combat viral infectious diseases.

Authors:  Shams Al-Azzam; Yun Ding; Jinsha Liu; Priyanka Pandya; Joey Paolo Ting; Sepideh Afshar
Journal:  Peptides       Date:  2020-09-01       Impact factor: 3.750

8.  Identification of miRNA-mRNA Crosstalk in Respiratory Syncytial Virus- (RSV-) Associated Pediatric Pneumonia through Integrated miRNAome and Transcriptome Analysis.

Authors:  Xu Zhang; Feng Huang; Diyuan Yang; Tao Peng; Gen Lu
Journal:  Mediators Inflamm       Date:  2020-05-01       Impact factor: 4.711

9.  Ribavirin efficiently suppresses porcine nidovirus replication.

Authors:  Youngnam Kim; Changhee Lee
Journal:  Virus Res       Date:  2012-10-27       Impact factor: 3.303

Review 10.  Chikungunya virus: an update on antiviral development and challenges.

Authors:  Parveen Kaur; Justin Jang Hann Chu
Journal:  Drug Discov Today       Date:  2013-05-15       Impact factor: 7.851

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