Literature DB >> 14742227

Safety and efficacy of antimicrobial peptides against naturally acquired leishmaniasis.

J Alberola1, A Rodríguez, O Francino, X Roura, L Rivas, D Andreu.   

Abstract

Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

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Year:  2004        PMID： 14742227      PMCID： PMC321547          DOI： 10.1128/AAC.48.2.641-643.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  33 in total

Review 1.  Current status of defensins and their role in innate and adaptive immunity.

Authors:  Periathamby Antony Raj; Andrew R Dentino
Journal:  FEMS Microbiol Lett       Date:  2002-01-02       Impact factor: 2.742

2.  Antimicrobial peptides of multicellular organisms.

Authors:  Michael Zasloff
Journal:  Nature       Date:  2002-01-24       Impact factor: 49.962

3.  N-terminal fatty acid substitution increases the leishmanicidal activity of CA(1-7)M(2-9), a cecropin-melittin hybrid peptide.

Authors:  C Chicharro; C Granata; R Lozano; D Andreu; L Rivas
Journal:  Antimicrob Agents Chemother       Date:  2001-09       Impact factor: 5.191

Review 4.  Mammalian defensins in immunity: more than just microbicidal.

Authors:  De Yang; Arya Biragyn; Larry W Kwak; Joost J Oppenheim
Journal:  Trends Immunol       Date:  2002-06       Impact factor: 16.687

5.  Antimicrobial peptides are signaling molecules.

Authors:  Michel Salzet
Journal:  Trends Immunol       Date:  2002-06       Impact factor: 16.687

6.  Structural requirements for potent versus selective cytotoxicity for antimicrobial dermaseptin S4 derivatives.

Authors:  Irina Kustanovich; Deborah E Shalev; Masha Mikhlin; Leonid Gaidukov; Amram Mor
Journal:  J Biol Chem       Date:  2002-02-14       Impact factor: 5.157

7.  Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: an outstanding candidate marker to predict the response to endocrine therapy.

Authors:  I Bieche; B Parfait; V Le Doussal; M Olivi; M C Rio; R Lidereau; M Vidaud
Journal:  Cancer Res       Date:  2001-02-15       Impact factor: 12.701

8.  Mapping and sequencing of the canine NRAMP1 gene and identification of mutations in leishmaniasis-susceptible dogs.

Authors:  Laura Altet; Olga Francino; Laia Solano-Gallego; Corinne Renier; Armand Sánchez
Journal:  Infect Immun       Date:  2002-06       Impact factor: 3.441

9.  Isolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family.

Authors:  P I Silva; S Daffre; P Bulet
Journal:  J Biol Chem       Date:  2000-10-27       Impact factor: 5.157

10.  Long term improvement in the treatment of canine leishmaniosis using an antimony liposomal formulation.

Authors:  J E Valladares; C Riera; P González-Ensenyat; A Díez-Cascón; G Ramos; L Solano-Gallego; M Gállego; M Portús; M Arboix; J Alberola
Journal:  Vet Parasitol       Date:  2001-05-09       Impact factor: 2.738
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  18 in total

1.  Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides.

Authors:  Rafael Ferre; Esther Badosa; Lidia Feliu; Marta Planas; Emili Montesinos; Eduard Bardají
Journal:  Appl Environ Microbiol       Date:  2006-05       Impact factor: 4.792

Review 2.  Peptide antimicrobial agents.

Authors:  Håvard Jenssen; Pamela Hamill; Robert E W Hancock
Journal:  Clin Microbiol Rev       Date:  2006-07       Impact factor: 26.132

3.  Synergistic effects of the membrane actions of cecropin-melittin antimicrobial hybrid peptide BP100.

Authors:  Rafael Ferre; Manuel N Melo; Ana D Correia; Lidia Feliu; Eduard Bardají; Marta Planas; Miguel Castanho
Journal:  Biophys J       Date:  2009-03-04       Impact factor: 4.033

4.  Efficacy of synthetic peptides RP-1 and AA-RP-1 against Leishmania species in vitro and in vivo.

Authors:  Marie Crisel B Erfe; Consuelo V David; Cher Huang; Victoria Lu; Ana Claudia Maretti-Mira; Jacquelyn Haskell; Kevin W Bruhn; Michael R Yeaman; Noah Craft
Journal:  Antimicrob Agents Chemother       Date:  2011-11-28       Impact factor: 5.191

5.  Enhanced resistance to the rice blast fungus Magnaporthe grisea conferred by expression of a cecropin A gene in transgenic rice.

Authors:  María Coca; Gisela Peñas; Jorge Gómez; Sonia Campo; Cristina Bortolotti; Joaquima Messeguer; Blanca San Segundo
Journal:  Planta       Date:  2005-10-21       Impact factor: 4.116

6.  Leishmania infection: laboratory diagnosing in the absence of a "gold standard".

Authors:  Alhelí Rodríguez-Cortés; Ana Ojeda; Olga Francino; Laura López-Fuertes; Marcos Timón; Jordi Alberola
Journal:  Am J Trop Med Hyg       Date:  2010-02       Impact factor: 2.345

7.  Anti-trypanosomatid activity of ceragenins.

Authors:  Diana Lara; Yanshu Feng; Julia Bader; Paul B Savage; Rosa A Maldonado
Journal:  J Parasitol       Date:  2010-06       Impact factor: 1.276

8.  Lysine-enriched cecropin-mellitin antimicrobial peptides with enhanced selectivity.

Authors:  Hiromi Sato; Jimmy B Feix
Journal:  Antimicrob Agents Chemother       Date:  2008-10-13       Impact factor: 5.191

9.  Killing of Trypanozoon Parasites by the Equine Cathelicidin eCATH1.

Authors:  S Cauchard; N Van Reet; P Büscher; D Goux; J Grötzinger; M Leippe; V Cattoir; C Laugier; J Cauchard
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

Review 10.  Emerging therapeutic targets for treatment of leishmaniasis.

Authors:  Shyam Sundar; Bhawana Singh
Journal:  Expert Opin Ther Targets       Date:  2018-05-09       Impact factor: 6.902
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