| Literature DB >> 14742225 |
M Kelli Jordan1, Aaron H Burstein, Diane Rock-Kress, Raul M Alfaro, Alice K Pau, Joseph A Kovacs, Stephen C Piscitelli.
Abstract
The pharmacokinetics of 2,000 mg of sulfadiazine administered twice daily (BID) versus those of 1,000 mg administered four times a day were compared in eight human immunodeficiency virus-infected patients. No differences in pharmacokinetic parameters were detected between the regimens. These data provide a pharmacokinetic rationale for BID dosing of sulfadiazine for the treatment and suppression of toxoplasmosis.Entities:
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Year: 2004 PMID: 14742225 PMCID: PMC321534 DOI: 10.1128/AAC.48.2.635-637.2004
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191