Literature DB >> 14741565

[18F]-2-fluoro-2-deoxyglucose transport kinetics as a function of extracellular glucose concentration in malignant glioma, fibroblast and macrophage cells in vitro.

Robert C Burrows1, Scott D Freeman, Aaron W Charlop, Robert W Wiseman, Tom C H Adamsen, Kenneth A Krohn, Alexander M Spence.   

Abstract

FDG-PET is used to measure the metabolic rate of glucose. Transport and phosphorylation determine the amount of hexose analog that is phosphorylated and trapped. Competition occurs for both events, such that extracellular glucose concentration affects the FDG image. This study investigated the effect of glucose concentration on the rate of FDG accumulation in three cell lines. The results show that extracellular glucose concentration has a greater impact on the rate of FDG accumulation than the relative abundance of GLUT transporter subtypes.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14741565     DOI： 10.1016/s0969-8051(02)00449-3

Source DB:  PubMed          Journal:  Nucl Med Biol        ISSN： 0969-8051            Impact factor:   2.408


  9 in total

1.  Computational modeling of adherent cell growth in a hollow-fiber membrane bioreactor for large-scale 3-D bone tissue engineering.

Authors:  Davod Mohebbi-Kalhori; Amin Behzadmehr; Charles J Doillon; Afra Hadjizadeh
Journal:  J Artif Organs       Date:  2012-05-19       Impact factor: 1.731

2.  In silico kinetic study of the glucose transporter.

Authors:  G L Alonso; D A González
Journal:  J Biol Phys       Date:  2008-08-15       Impact factor: 1.365

3.  The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ.

Authors:  Rui Appelberg; Diana Moreira; Palmira Barreira-Silva; Margarida Borges; Letícia Silva; Ricardo Jorge Dinis-Oliveira; Mariana Resende; Margarida Correia-Neves; Michael B Jordan; Nuno C Ferreira; Antero J Abrunhosa; Ricardo Silvestre
Journal:  Immunology       Date:  2015-04-20       Impact factor: 7.397

4.  Targeting presynaptic norepinephrine transporter in brown adipose tissue: a novel imaging approach and potential treatment for diabetes and obesity.

Authors:  M Reza Mirbolooki; Cristian C Constantinescu; Min-Liang Pan; Jogeshwar Mukherjee
Journal:  Synapse       Date:  2012-11-08       Impact factor: 2.562

5.  The power of FDG-PET to detect treatment effects is increased by glucose correction using a Michaelis constant.

Authors:  Simon-Peter Williams; Judith E Flores-Mercado; Andreas R Baudy; Ruediger E Port; Thomas Bengtsson
Journal:  EJNMMI Res       Date:  2012-06-27       Impact factor: 3.138

6.  Quantitation of glucose uptake in tumors by dynamic FDG-PET has less glucose bias and lower variability when adjusted for partial saturation of glucose transport.

Authors:  Simon-Peter Williams; Judith E Flores-Mercado; Ruediger E Port; Thomas Bengtsson
Journal:  EJNMMI Res       Date:  2012-02-01       Impact factor: 3.138

7.  Differences in in vitro microglial accumulation of the energy metabolism tracers [18F]FDG and [18F]BCPP-EF during LPS- and IL4 stimulation.

Authors:  Chie Suzuki; Sarina Han; Gandhervin Kesavamoorthy; Mutsumi Kosugi; Kaori Araki; Norihiro Harada; Masakatsu Kanazawa; Hideo Tsukada; Yasuhiro Magata; Yasuomi Ouchi
Journal:  Sci Rep       Date:  2021-06-24       Impact factor: 4.379

8.  Does 2-FDG PET Accurately Reflect Quantitative In Vivo Glucose Utilization?

Authors:  Jorge R Barrio; Sung-Cheng Huang; Nagichettiar Satyamurthy; Claudio S Scafoglio; Amy S Yu; Abass Alavi; Kenneth A Krohn
Journal:  J Nucl Med       Date:  2019-11-01       Impact factor: 11.082

9.  [18F]2-fluoro-2-deoxy-D-glucose incorporation by AGS gastric adenocarcinoma cells in vitro during response to epirubicin, cisplatin and 5-fluorouracil.

Authors:  S A Suttie; K G M Park; T A D Smith
Journal:  Br J Cancer       Date:  2007-09-11       Impact factor: 7.640
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.