| Literature DB >> 14741412 |
Jiajun Shi1, Sizhong Zhang, Mouni Tang, Xiehe Liu, Tao Li, Haiying Han, Yingcheng Wang, Yangbo Guo, Jinghua Zhao, Hai Li, Cui Ma.
Abstract
The common polymorphism at codon 311 (C311S) of paraoxonase 2 gene (PON2) was investigated in 165 patients with sporadic late-onset Alzheimer's disease (LOAD) and 174 controls in Chinese. The PON2*C allele frequency was significantly increased in the patients as compared with controls. However, no significant difference was observed after stratification of apolipoprotein E (ApoE) epsilon4 allele. These results suggested that the PON2 polymorphism might be a risk factor for LOAD independent of ApoE epsilon4 status in Chinese.Entities:
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Year: 2004 PMID： 14741412 DOI： 10.1016/j.molbrainres.2003.10.018
Source DB: PubMed Journal: Brain Res Mol Brain Res ISSN： 0169-328X