| Literature DB >> 14741267 |
Christopher G Thomson1, Margaret S Beer, Neil R Curtis, Helen J Diggle, Emma Handford, Janusz J Kulagowski.
Abstract
A series of thiazole based 5HT(7) ligands has been identified from screening. Optimisation of the pendent aryl group and modification of the core gave a related series of high affinity, selective thiopyridine based 5HT(7) ligands, the most active of which behaves as a partial agonist.Entities:
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Year: 2004 PMID： 14741267 DOI： 10.1016/j.bmcl.2003.11.050
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823