| Literature DB >> 14741262 |
Truong Phuong1, Thai Khac-Minh, Nguyen Thi Van Ha, Huynh Thi Ngoc Phuong.
Abstract
A total of 20 new phenylenedithiourea derivatives was synthesized by reaction of phenylenediisothiocyanates with aromatic amines as aminobenzoic, aminosalicylic acid and their derivatives. Their chemical structures were confirmed by elemental analysis, IR spectrometry and 1H NMR. The compounds were screened for in vitro antifungal, antibacterial activities and some of them have strong antifungal activities comparable to the activity observed for ketoconazole.Entities:
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Year: 2004 PMID： 14741262 DOI： 10.1016/j.bmcl.2003.11.044
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823