Literature DB >> 14740034

Thioglycosynthases: double mutant glycosidases that serve as scaffolds for thioglycoside synthesis.

Michael Jahn1, Hongming Chen, Johannes Müllegger, Jennifer Marles, R Antony J Warren, Stephen G Withers.   

Abstract

A double mutant, retaining glycosidase that lacks both the catalytic nucleophile and the catalytic acid/base residues efficiently catalyzes thioglycoside formation from a glycosyl fluoride donor and thiosugar acceptors.

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Year:  2004        PMID： 14740034     DOI： 10.1039/b313155f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Streamlined Iterative Assembly of Thio-Oligosaccharides by Aqueous S-Glycosylation of Diverse Deoxythio Sugars.

Authors:  Peng Wen; Peijing Jia; Qiuhua Fan; Bethany J McCarty; Weiping Tang
Journal:  ChemSusChem       Date:  2022-01-10       Impact factor: 9.140

2.  The glycosyltransferase involved in thurandacin biosynthesis catalyzes both O- and S-glycosylation.

Authors:  Huan Wang; Trent J Oman; Ran Zhang; Chantal V Garcia De Gonzalo; Qi Zhang; Wilfred A van der Donk
Journal:  J Am Chem Soc       Date:  2013-12-16       Impact factor: 15.419

3.  Probing the role of an invariant active site His in family GH1 β-glycosidases.

Authors:  Andrea Strazzulli; Giuseppe Perugino; Marialuisa Mazzone; Mosè Rossi; Stephen G Withers; Marco Moracci
Journal:  J Enzyme Inhib Med Chem       Date:  2019-12       Impact factor: 5.051
  3 in total

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