| Literature DB >> 14739084 |
Abstract
We investigate a simple model that generates random partitions of the leaf set of a tree. Of particular interest is the reconstruction question: what number k of independent samples (partitions) are required to correctly reconstruct the underlying tree (with high probability)? We demonstrate a phase transition for k as a function of the mutation rate, from logarithmic to polynomial dependence on the size of the tree. We also describe a simple polynomial-time tree reconstruction algorithm that applies in the logarithmic region. This model and the associated reconstruction questions are motivated by a Markov model for genomic evolution in molecular biology.Entities:
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Year: 2004 PMID: 14739084 DOI: 10.1016/j.mbs.2003.10.004
Source DB: PubMed Journal: Math Biosci ISSN: 0025-5564 Impact factor: 2.144