| Literature DB >> 14739073 |
Joan Tordjman1, Wael Khazen, Bénédicte Antoine, Geneviève Chauvet, Joelle Quette, Françoise Fouque, Elmus G Beale, Chantal Benelli, Claude Forest.
Abstract
Recent studies brought adipocyte glyceroneogenesis back to the fore as an important pathway in fatty acid homeostasis and underlined the key role played by cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) in this pathway. The present review analyses the mechanisms by which a series of hormones and nutrients affect PEPCK-C gene transcription and glyceroneogenesis and describes evidence for disregulation of this pathway in type 2 diabetes.Entities:
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Year: 2003 PMID： 14739073 DOI： 10.1016/j.biochi.2003.11.010
Source DB: PubMed Journal: Biochimie ISSN： 0300-9084 Impact factor: 4.079