Literature DB >> 14738397

Immunomodulatory constituents from an Ascomycete, Chaetomium seminudum.

Haruhiro Fujimoto1, Megumi Sumino, Emi Okuyama, Masami Ishibashi.   

Abstract

A screening study focusing on immunomodulatory activity of the EtOAc extract of an Ascomycete, Chaetomium seminudum, has afforded a known epipolythiodioxopiperazine, chetomin (1), together with three new chetomin-related metabolites named chetoseminudins A (2), B (3), and C (4). Among these four metabolites, 1 and 2 have been deduced as the immunosuppressive features of this fungus.

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Year:  2004        PMID： 14738397     DOI： 10.1021/np0302201

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  16 in total

1.  Polymorphism and phase transition behavior of 6,6'-bis(chloromethyl)-1,1',4,4'-tetramethyl-3,3'-(p-phenylenedimethylene)bis(piperazine-2,5-dione).

Authors:  Nathan W Polaske; Gary S Nichol; Bogdan Olenyuk
Journal:  Acta Crystallogr C       Date:  2009-07-09       Impact factor: 1.172

2.  A Modular Construction of Epidithiodiketopiperazines.

Authors:  Thomas N Snaddon; Toya D Scaggs; Colin M Pearson; James W B Fyfe
Journal:  Org Lett       Date:  2019-06-11       Impact factor: 6.005

3.  Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.

Authors:  Katharine R Watts; Joseline Ratnam; Kean-Hooi Ang; Karen Tenney; Jennifer E Compton; James McKerrow; Phillip Crews
Journal:  Bioorg Med Chem       Date:  2010-03-01       Impact factor: 3.641

4.  Enantioselective organocatalytic alpha-sulfenylation of substituted diketopiperazines.

Authors:  Nathan W Polaske; Ramin Dubey; Gary S Nichol; Bogdan Olenyuk
Journal:  Tetrahedron Asymmetry       Date:  2009-12-11

5.  Efficient Organocatalytic alpha-Sulfenylation of Substituted Piperazine-2,5-diones.

Authors:  Ramin Dubey; Nathan W Polaske; Gary S Nichol; Bogdan Olenyuk
Journal:  Tetrahedron Lett       Date:  2009-07-29       Impact factor: 2.415

Review 6.  Epidithiodioxopiperazines. occurrence, synthesis and biogenesis.

Authors:  Timothy R Welch; Robert M Williams
Journal:  Nat Prod Rep       Date:  2014-10       Impact factor: 13.423

7.  Diethyl trans-2,5-bis-(4-methoxy-benzyl-sulfan-yl)-1,4-dimethyl-3,6-dioxopiperazine-2,5-carboxyl-ate.

Authors:  Nathan W Polaske; Gary S Nichol; Bogdan Olenyuk
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-06-17

8.  Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.

Authors:  Masatsugu Hiraki; So-Young Hwang; Shugeng Cao; Timothy R Ramadhar; Sanguine Byun; Kyoung Wan Yoon; Jung Hyun Lee; Kiki Chu; Aditi U Gurkar; Vihren Kolev; Jianming Zhang; Takushi Namba; Maureen E Murphy; David J Newman; Anna Mandinova; Jon Clardy; Sam W Lee
Journal:  Chem Biol       Date:  2015-08-27

Review 9.  Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).

Authors:  Dale G Nagle; Yu-Dong Zhou
Journal:  Curr Drug Targets       Date:  2006-03       Impact factor: 3.465

10.  Indole diketopiperazines from endophytic Chaetomium sp 88194 induce breast cancer cell apoptotic death.

Authors:  Fu-qian Wang; Qing-yi Tong; Hao-ran Ma; Hong-feng Xu; Song Hu; Wei Ma; Yong-bo Xue; Jun-jun Liu; Jian-ping Wang; Hong-ping Song; Jin-wen Zhang; Geng Zhang; Yong-hui Zhang
Journal:  Sci Rep       Date:  2015-03-19       Impact factor: 4.379
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