| Literature DB >> 1473557 |
E Spreafico1, E Bettini, G Pollio, A Maggi.
Abstract
The cDNA of the Sprague-Dawley rat estrogen receptor was sequenced. With respect to the published Wistar rat estrogen receptor sequence, a single amino acid difference (tryptophan instead of asparagine) was found in the hormone binding site. Since tryptophan was found at the same position in chicken, human and mouse estrogen receptors, it is proposed that the Wistar rat could represent an interesting natural mutant for estrogen receptor studies.Entities:
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Year: 1992 PMID： 1473557 DOI： 10.1016/0922-4106(92)90016-o
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432