Literature DB >> 14735373

Abnormal uterine bleeding as a presentation of metastatic breast disease in a patient with advanced breast cancer on tamoxifen therapy.

Akin Famoriyo1, Sangeeta Sawant, Phillip J Banfield.   

Abstract

INTRODUCTION: Extra pelvic tumours rarely metastasise to the female genital tract. Typically it is the ovaries that are involved and the primary tumours include the breast and the gastrointestinal tract. Metastatic disease involving the uterus is rare. CASE REPORT: A case of metastatic breast carcinoma involving both the uterine corpus and cervix is described. The patient was known to have advanced breast carcinoma and was on tamoxifen therapy when she presented with postmenopausal bleeding. Histological assessment of the hysterectomy specimen including immunohistochemistry staining confirmed the breast carcinoma as the primary.
CONCLUSION: Unusual uterine bleeding in a patient with breast cancer, should alert the gynaecologist to the possibility of metastatic breast disease regardless of tamoxifen treatment.

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Year:  2004        PMID: 14735373     DOI: 10.1007/s00404-003-0500-2

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  4 in total

1.  Recurrent breast carcinoma presenting as postmenopausal vaginal bleeding: A case report.

Authors:  Anna Binstock; Ashlee L Smith; Alexander B Olawaiye
Journal:  Gynecol Oncol Rep       Date:  2013-06-24

2.  Unusual uterine metastasis of invasive ductal carcinoma: A case report.

Authors:  Tayfur Çift; Berna Aslan; Berk Bulut; Şennur İlvan
Journal:  Turk J Obstet Gynecol       Date:  2016-09-15

3.  An Unusual Occurrence of Uterine Metastases in a Case of Invasive Ductal Breast Carcinoma.

Authors:  Musa Azhar; Syed Abdul Mannan Hamdani; Jhanzeb Iftikhar; Waqas Ahmad; Sajid Mushtaq; Umm-E Kalsoom Awan
Journal:  Cureus       Date:  2021-11-22

4.  Lobular breast carcinoma metastatic to the endometrium in a patient under tamoxifen therapy: A case report.

Authors:  Mariangela Gomez; Kerry Whitting; Rana Naous
Journal:  SAGE Open Med Case Rep       Date:  2020-02-16
  4 in total

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