Literature DB >> 1473521

Quantitative analyses of urinary pyridinoline and deoxypyridinoline excretion in patients with hyperthyroidism.

T Ohishi1, M Takahashi, K Kushida, K Horiuchi, S Ishigaki, T Inoue.   

Abstract

It is well established that bone turnover increases and bone resorption exceeds bone formation in patients with hyperthyroidism. Recently, urinary pyridinoline and deoxypyridinoline have been employed as indicators of bone resorption. In this study, urinary pyridinoline and deoxypyridinoline levels in fourteen female patients with untreated hyperthyroidism were measured and compared with levels in 134 healthy females. Values of urinary pyridinoline and deoxypyridinoline were significantly higher than in age-matched controls. Moreover, values of serum free triiodothyronine correlated with urinary pyridinoline (r = 0.769, p < 0.01), and urinary deoxypyridinoline (r = 0.799, p < 0.001) in patients with hyperthyroidism.

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Year:  1992        PMID: 1473521     DOI: 10.1080/07435809209111037

Source DB:  PubMed          Journal:  Endocr Res        ISSN: 0743-5800            Impact factor:   1.720


  6 in total

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Review 5.  Potential of biomarkers during pharmacological therapy setting for postmenopausal osteoporosis: a systematic review.

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6.  Urinary pyridinoline and deoxypyridinoline in prostate carcinoma patients with bone metastasis.

Authors:  M Sano; K Kushida; M Takahashi; T Ohishi; K Kawana; M Okada; T Inoue
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  6 in total

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