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Literature DB >> 14732690

The ins and outs of presenilin 1 membrane topology.

Jinoh Kim¹, Randy Schekman.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2004 PMID： 14732690 PMCID： PMC327113 DOI： 10.1073/pnas.0307297101

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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21 in total

1. The presenilins turned inside out: implications for their structures and functions.

Authors: Nazneen N Dewji; Dante Valdez; S J Singer
Journal: Proc Natl Acad Sci U S A Date: 2004-01-19 Impact factor: 11.205

2. Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1.

Authors: M A Navia; P M Fitzgerald; B M McKeever; C T Leu; J C Heimbach; W K Herber; I S Sigal; P L Darke; J P Springer
Journal: Nature Date: 1989-02-16 Impact factor: 49.962

3. Membrane topology of the C. elegans SEL-12 presenilin.

Authors: X Li; I Greenwald
Journal: Neuron Date: 1996-11 Impact factor: 17.173

4. Inversion of the membrane topology of SecG coupled with SecA-dependent preprotein translocation.

Authors: K Nishiyama; T Suzuki; H Tokuda
Journal: Cell Date: 1996-04-05 Impact factor: 41.582

5. The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

Authors: C A Saura; T Tomita; S Soriano; M Takahashi; J Y Leem; T Honda; E H Koo; T Iwatsubo; G Thinakaran
Journal: J Biol Chem Date: 2000-06-02 Impact factor: 5.157

6. Reconstitution of gamma-secretase activity.

Authors: Dieter Edbauer; Edith Winkler; Joerg T Regula; Brigitte Pesold; Harald Steiner; Christian Haass
Journal: Nat Cell Biol Date: 2003-05 Impact factor: 28.824

7. Protein topology of presenilin 1.

Authors: A Doan; G Thinakaran; D R Borchelt; H H Slunt; T Ratovitsky; M Podlisny; D J Selkoe; M Seeger; S E Gandy; D L Price; S S Sisodia
Journal: Neuron Date: 1996-11 Impact factor: 17.173

Review 8. Genetic dissection of Alzheimer disease, a heterogeneous disorder.

Authors: G D Schellenberg
Journal: Proc Natl Acad Sci U S A Date: 1995-09-12 Impact factor: 11.205

9. Membrane insertion and assembly of ductin: a polytopic channel with dual orientations.

Authors: J Dunlop; P C Jones; M E Finbow
Journal: EMBO J Date: 1995-08-01 Impact factor: 11.598

10. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing.

Authors: S Soriano; D E Kang; M Fu; R Pestell; N Chevallier; H Zheng; E H Koo
Journal: J Cell Biol Date: 2001-02-19 Impact factor: 10.539

7 in total

1. Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis.

Authors: Mikhail Bogdanov; Wei Zhang; Jun Xie; William Dowhan
Journal: Methods Date: 2005-06 Impact factor: 3.608

The ins and outs of presenilin 1 membrane topology.

1. The presenilins turned inside out: implications for their structures and functions.

2. Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1.

3. Membrane topology of the C. elegans SEL-12 presenilin.

4. Inversion of the membrane topology of SecG coupled with SecA-dependent preprotein translocation.

5. The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

6. Reconstitution of gamma-secretase activity.

7. Protein topology of presenilin 1.

Review 8. Genetic dissection of Alzheimer disease, a heterogeneous disorder.

9. Membrane insertion and assembly of ductin: a polytopic channel with dual orientations.

10. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing.

1. Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis.

2. Evidence that the COOH terminus of human presenilin 1 is located in extracytoplasmic space.

Review 3. Gamma-secretase catalyzes sequential cleavages of the AbetaPP transmembrane domain.

Review 4. APP processing in Alzheimer's disease.

Review 5. Trafficking regulation of proteins in Alzheimer's disease.

Review 6. The γ-secretase complex: from structure to function.

Review 7. The very many faces of presenilins and the γ-secretase complex.