Literature DB >> 14731863

Nuclear pre-mRNA metabolism: channels and tracks.

J Kramer1, Z Zachar, P M Bingham.   

Abstract

We review new evidence suggesting that metazoan nuclear pre-mRNA metabolism occurs in a small subnuclear compartment consisting of a network of channels defined by exclusion from various condensed structures. Nuclear components, including mRNA en route from the gene to the nuclear surface, apparently move through these channels by conventional diffusion.

Year:  1994        PMID： 14731863     DOI： 10.1016/0962-8924(94)90001-9

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  8 in total

1.  The functional architecture of the nucleus as analysed by ultrastructural cytochemistry.

Authors:  Stanislav Fakan
Journal:  Histochem Cell Biol       Date:  2004-08-05       Impact factor: 4.304

2.  Functional structure of the cell nucleus.

Authors:  Pavel Hozák; Stan Fakan
Journal:  Histochem Cell Biol       Date:  2005-10-27       Impact factor: 4.304

3.  Splicing components are excluded from the transcriptionally inactive XY body in male meiotic nuclei.

Authors:  C Richler; G Ast; R Goitein; J Wahrman; R Sperling; J Sperling
Journal:  Mol Biol Cell       Date:  1994-12       Impact factor: 4.138

Review 4.  The Tpr protein: linking structure and function in the nuclear interior?

Authors:  M R Paddy
Journal:  Am J Hum Genet       Date:  1998-08       Impact factor: 11.025

5.  Organization of highly acetylated chromatin around sites of heterogeneous nuclear RNA accumulation.

Authors:  M J Hendzel; M J Kruhlak; D P Bazett-Jones
Journal:  Mol Biol Cell       Date:  1998-09       Impact factor: 4.138

6.  Polytene chromosomes show normal gene activity but some mRNAs are abnormally accumulated in the pseudonurse cell nuclei of Drosophila melanogaster otu mutants.

Authors:  T I Heino; V P Lahti; M Tirronen; C Roos
Journal:  Chromosoma       Date:  1995-10       Impact factor: 4.316

Review 7.  Organization of (pre-)mRNA metabolism in the cell nucleus.

Authors:  D G Wansink; R van Driel; L de Jong
Journal:  Mol Biol Rep       Date:  1994       Impact factor: 2.316

8.  Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain.

Authors:  C Johnson; D Primorac; M McKinstry; J McNeil; D Rowe; J B Lawrence
Journal:  J Cell Biol       Date:  2000-08-07       Impact factor: 10.539
  8 in total

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