Literature DB >> 14731846

Cellular substrates of p34(cdc2) and its companion cyclin-dependent kinases.

E A Nigg1.   

Abstract

Cyclin-dependent kinase (cdks) are key components of the engine that drives the cell proliferation cycle in all eukaryotes. These kinases are related to p34(cdc2) and associate with regulatory subunits belonging to the cyclin family. To understand how cdks promote cell cycle progression, it will be important to identify their physiological substrates and to determine how phosphorylation influences the functions of these substrates. This article discusses recent progress as well as some of the problems related to the quest for cdk substrates.

Entities:  

Year:  1993        PMID： 14731846     DOI： 10.1016/0962-8924(93)90011-o

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  92 in total

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Journal:  EMBO J       Date:  2001-03-15       Impact factor: 11.598

2.  BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site.

Authors:  H Ruffner; W Jiang; A G Craig; T Hunter; I M Verma
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

Review 3.  Factors controlling cyclin B expression.

Authors:  M Ito
Journal:  Plant Mol Biol       Date:  2000-08       Impact factor: 4.076

4.  Growth inhibition of human glioma cells by transfection-induced P21 and its effects on telomerase activity.

Authors:  K Harada; K Kurisu; T Sadatomo; H Tahara; E Tahara; T Ide; E Tahara
Journal:  J Neurooncol       Date:  2000-03       Impact factor: 4.130

5.  Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

Authors:  I Vincent; G Jicha; M Rosado; D W Dickson
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

6.  CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication.

Authors:  Muluye E Liku; Van Q Nguyen; Audrey W Rosales; Kaoru Irie; Joachim J Li
Journal:  Mol Biol Cell       Date:  2005-08-10       Impact factor: 4.138

7.  Cig2, a B-type cyclin, promotes the onset of S in Schizosaccharomyces pombe.

Authors:  O Mondesert; C H McGowan; P Russell
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

8.  Cyclin B2 and p53 control proper timing of centrosome separation.

Authors:  Hyun-Ja Nam; Jan M van Deursen
Journal:  Nat Cell Biol       Date:  2014-04-28       Impact factor: 28.824

9.  Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation.

Authors:  Gergely Róna; Máté Borsos; Jonathan J Ellis; Ahmed M Mehdi; Mary Christie; Zsuzsanna Környei; Máté Neubrandt; Judit Tóth; Zoltán Bozóky; László Buday; Emília Madarász; Mikael Bodén; Bostjan Kobe; Beáta G Vértessy
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

10.  Phosphorylation of the Oxytricha telomere protein: possible cell cycle regulation.

Authors:  B Hicke; R Rempel; J Maller; R A Swank; J R Hamaguchi; E M Bradbury; D M Prescott; T R Cech
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971
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