Literature DB >> 14731796

Protein import into mitochondria: two systems acting in tandem?

B Glick1, C Wachter, G Schatz.   

Abstract

Mitochondria can import proteins from the cytoplasm at sites where the two mitochondrial membranes are closely apposed. However, each of these membranes contains a distinct protein translocation channel. Recent evidence suggests that the two types of channel are not permanently coupled, but may dissociate in a reversible manner. This reversible interaction is probably essential for intramitochondrial sorting proteins.

Year:  1991        PMID： 14731796     DOI： 10.1016/0962-8924(91)90037-a

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  23 in total

1.  Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b(2) import pathway.

Authors:  M Esaki; T Kanamori; S i Nishikawa; T Endo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-12       Impact factor: 11.205

Review 2.  MCC and PSC, the putative protein import channels of mitochondria.

Authors:  K W Kinnally; C Muro; M L Campo
Journal:  J Bioenerg Biomembr       Date:  2000-02       Impact factor: 2.945

Review 3.  Peroxisome biogenesis in Saccharomyces cerevisiae.

Authors:  W H Kunau; A Hartig
Journal:  Antonie Van Leeuwenhoek       Date:  1992-08       Impact factor: 2.271

4.  Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane.

Authors:  P E Scherer; U C Manning-Krieg; P Jenö; G Schatz; M Horst
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

5.  Biogenesis of Tim23 and Tim17, integral components of the TIM machinery for matrix-targeted preproteins.

Authors:  K Káldi; M F Bauer; C Sirrenberg; W Neupert; M Brunner
Journal:  EMBO J       Date:  1998-03-16       Impact factor: 11.598

6.  Topology of IEP110, a component of the chloroplastic protein import machinery present in the inner envelope membrane.

Authors:  J Lübeck; J Soll; M Akita; E Nielsen; K Keegstra
Journal:  EMBO J       Date:  1996-08-15       Impact factor: 11.598

7.  In vivo zippering of inner and outer mitochondrial membranes by a stable translocation intermediate.

Authors:  N Schülke; N B Sepuri; D Pain
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-08       Impact factor: 11.205

8.  Trial end points and natural history in patients with G11778A Leber hereditary optic neuropathy : preparation for gene therapy clinical trial.

Authors:  Byron L Lam; William J Feuer; Joyce C Schiffman; Vittorio Porciatti; Ruth Vandenbroucke; Potyra R Rosa; Giovanni Gregori; John Guy
Journal:  JAMA Ophthalmol       Date:  2014-04-01       Impact factor: 7.389

9.  RPM2, independently of its mitochondrial RNase P function, suppresses an ISP42 mutant defective in mitochondrial import and is essential for normal growth.

Authors:  C K Kassenbrock; G J Gao; K R Groom; P Sulo; M G Douglas; N C Martin
Journal:  Mol Cell Biol       Date:  1995-09       Impact factor: 4.272

10.  Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins.

Authors:  C M Koehler; S Merchant; W Oppliger; K Schmid; E Jarosch; L Dolfini; T Junne; G Schatz; K Tokatlidis
Journal:  EMBO J       Date:  1998-11-16       Impact factor: 11.598
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