| Literature DB >> 14731655 |
Abstract
Profilin, the prototype actin-monomer-sequestering protein, has recently emerged as a multifunctional protein with several different activities. Genetic evidence in yeast and flies confirms that profilin is required for a normal actin cytoskeleton, while biochemical evidence suggests a role in regulating phosphoinositide signalling. New studies suggest that profilin may interact with other ligands, and even its role in regulating actin polymerization is now being re-evaluated.Entities:
Year: 1993 PMID: 14731655 DOI: 10.1016/0962-8924(93)90087-h
Source DB: PubMed Journal: Trends Cell Biol ISSN: 0962-8924 Impact factor: 20.808