Literature DB >> 14731198

Paradoxical association between smoking and olfactory identification in psychosis versus controls.

Duncan McLean1, François Féron, Alan Mackay-Sim, Richard McCurdy, Madonna Hirning, David Chant, John McGrath.   

Abstract

OBJECTIVE: Deficits in olfactory identification have been demonstrated in patients with schizophrenia. This study examined the interaction between smoking and olfactory identification in patients with psychotic disorders versus well controls.
METHOD: Olfactory identification was assessed in three groups of subjects using the University of Pennsylvania Smell Identification Test (UPSIT). Sixteen patients with affective psychoses, 22 patients with nonaffective psychoses, and 21 well controls were tested.
RESULTS: There was a significant interaction between diagnostic classification (patient or control) and smoking. Patients who were smokers scored higher on the UPSIT than non-smokers, while controls who were smokers scored lower than non-smokers.
CONCLUSIONS: Smoking may have a 'normalising' effect on olfactory identification in some patients with psychosis. Further studies are needed to examine the relationship between psychosis, olfactory identification and the effects of nicotine.

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Year:  2004        PMID: 14731198     DOI: 10.1111/j.1440-1614.2004.01301.x

Source DB:  PubMed          Journal:  Aust N Z J Psychiatry        ISSN: 0004-8674            Impact factor:   5.744


  8 in total

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8.  Negative symptoms of schizophrenia correlate with impairment on the University of Pennsylvania smell identification test.

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  8 in total

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