Literature DB >> 14730995

A fluorescent intercalator displacement assay for establishing DNA binding selectivity and affinity.

Winston C Tse1, Dale L Boger.   

Abstract

A summary of the qualitative and quantitative elements of a fluorescent intercalator displacement (FID) assay useful for establishing the DNA binding selectivity, affinity, stoichiometry, and binding site size and distinguishing modes of DNA binding is provided.

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Year:  2004        PMID: 14730995     DOI: 10.1021/ar030113y

Source DB:  PubMed          Journal:  Acc Chem Res        ISSN: 0001-4842            Impact factor:   22.384


  59 in total

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8.  The effects of hairpin loops on ligand-DNA interactions.

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9.  The role of flexibility in the rational design of modularly assembled ligands targeting the RNAs that cause the myotonic dystrophies.

Authors:  Matthew D Disney; Melissa M Lee; Alexei Pushechnikov; Jessica L Childs-Disney
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10.  DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-Indole Antibiotics.

Authors:  Timothy J Opperman; Steven M Kwasny; Jessica Bo Li; Mark A Lewis; Daniel Aiello; John D Williams; Norton P Peet; Donald T Moir; Terry L Bowlin; Eric C Long
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