Literature DB >> 14730382

Appendicitis in children less than 3 years of age: a 28-year review.

Javed Alloo1, Theodore Gerstle, Joel Shilyansky, Sigmund H Ein.   

Abstract

Appendicitis is the most common surgical abdominal emergency in the pediatric population, but is rarely considered in children less than 3 years of age. The goal of this study was to identify the presenting symptoms and signs in this age group and examine their subsequent management and outcome. A 28-year experience of a single pediatric surgeon in academic practice was reviewed; 27 children less than 3 years old (mean 23 months) comprised 2.3% of all children with appendicitis in his series. The most common presenting symptoms were vomiting (27), fever (23), pain (21), anorexia (15), and diarrhea (11). The average duration of symptoms was 3 days, with 4 or more days in 9 children. Eighteen children were seen by a physician before the correct diagnosis was made; 14 were initially treated for an upper respiratory tract infection, otitis media, or a urinary tract infection. The most common presenting signs were abdominal tenderness (27), peritonitis (24), temperature 38.0 degrees C or more (21), abdominal distension (18), Leukocytosis (<12.0 x 10(3)/mm(3)) was found in 18, tenderness was localized to the right lower quadrant (RLQ) in 14 and was diffuse in 10. Abdominal radiographs demonstrated findings of a small-bowel obstruction (SBO) in 14 of 21 patients, a fecalith in 2, and a pneumoperitoneum in 1. Contrast enemas were performed in 6 children, 5 of whom had a phlegmon or an abscess. Perforated appendicitis was found in all 27 patients. An appendectomy was performed in 25 and a RLQ drain was placed in 18. Postoperative antibiotics were administered to 17 children for an average of 6 days. Two patients underwent interval appendectomies, 1 following treatment with IV antibiotics and 1 following surgical drainage. The average time to resume oral intake was 7 days and the average hospital stay was 21 (median 15) days. Sixteen patients had 22 complications, which included 6 wound infections, 4 abscesses, 4 wound dehiscences, 3 pneumonias, 2 SBOs, 2 incisional hernias, and 1 enterocutaneous fistula. Perforated appendicitis was found in all children less than 3 years old, resulting in very high morbidity (59% complications), which may be attributed to the 3-5-day delay in diagnosis. Although appendicitis is uncommon in this age group, it should be seriously considered in the differential diagnosis of children under the age of 3 years who present with the triad of abdominal pain, tenderness, and vomiting.

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Year:  2004        PMID: 14730382     DOI: 10.1007/s00383-002-0775-6

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  14 in total

1.  Index of suspicion. Case 1. Omental torsion.

Authors:  R A Lawrence
Journal:  Pediatr Rev       Date:  1999-04

2.  Grunting respirations: chest or abdominal pathology?

Authors:  J I Singer; J D Losek
Journal:  Pediatr Emerg Care       Date:  1992-12       Impact factor: 1.454

3.  Helical CT technique for the diagnosis of appendicitis: prospective evaluation of a focused appendix CT examination.

Authors:  P M Rao; J T Rhea; R A Novelline; C J McCabe; J N Lawrason; D L Berger; R Sacknoff
Journal:  Radiology       Date:  1997-01       Impact factor: 11.105

4.  Acute appendicitis: influence of early pain relief on the accuracy of clinical and US findings in the decision to operate--a randomized trial.

Authors:  B Vermeulen; A Morabia; P F Unger; C Goehring; C Grangier; I Skljarov; F Terrier
Journal:  Radiology       Date:  1999-03       Impact factor: 11.105

5.  Selective use of ultrasonography for acute appendicitis in children.

Authors:  M S Lessin; M Chan; M Catallozzi; M F Gilchrist; C Richards; L Manera; M T Wallach; F I Luks
Journal:  Am J Surg       Date:  1999-03       Impact factor: 2.565

Review 6.  Acute abdominal pain in children.

Authors:  M Davenport
Journal:  BMJ       Date:  1996-02-24

7.  Rapid detection of acute appendicitis with Tc-99m-labeled intact polyvalent human immune globulin.

Authors:  D W Wong; P Vasinrapee; M E Spieth; R E Cook; A N Ansari; M Jones; A Mandal
Journal:  J Am Coll Surg       Date:  1997-12       Impact factor: 6.113

8.  Importance of diarrhea as a presenting symptom of appendicitis in very young children.

Authors:  J R Horwitz; M Gursoy; T Jaksic; K P Lally
Journal:  Am J Surg       Date:  1997-02       Impact factor: 2.565

Review 9.  The approach to common abdominal diagnosis in infants and children.

Authors:  M S Irish; R H Pearl; M G Caty; P L Glick
Journal:  Pediatr Clin North Am       Date:  1998-08       Impact factor: 3.278

10.  Pediatric appendicitis: efficacy of laboratory and radiologic evaluation.

Authors:  D L Mollitt; D Mitchum; J J Tepas
Journal:  South Med J       Date:  1988-12       Impact factor: 0.954

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  17 in total

1.  Conservative treatment in uncomplicated acute appendicitis: reassessment of practice safety.

Authors:  Zvi Steiner; Genady Buklan; Rodica Stackievicz; Michael Gutermacher; Ita Litmanovitz; Guy Golani; Shmuel Arnon
Journal:  Eur J Pediatr       Date:  2017-02-16       Impact factor: 3.183

2.  Seasonal and day of the week variations of perforated appendicitis in US children.

Authors:  Yi Deng; David C Chang; Yiyi Zhang; Jennifer Webb; Alodia Gabre-Kidan; Fizan Abdullah
Journal:  Pediatr Surg Int       Date:  2010-06-04       Impact factor: 1.827

Review 3.  Pediatric appendicitis: state of the art review.

Authors:  Rebecca M Rentea; Shawn D St Peter; Charles L Snyder
Journal:  Pediatr Surg Int       Date:  2016-10-14       Impact factor: 1.827

4.  The impact of disease severity, age and surgical approach on the outcome of acute appendicitis in children.

Authors:  A L van den Boom; R R Gorter; P M M van Haard; P G Doornebosch; H A Heij; I Dawson
Journal:  Pediatr Surg Int       Date:  2015-02-17       Impact factor: 1.827

5.  Prevention of infectious complications after laparoscopic appendectomy for complicated acute appendicitis--the role of routine abdominal drainage.

Authors:  Pierre Allemann; Herve Probst; Nicolas Demartines; Markus Schäfer
Journal:  Langenbecks Arch Surg       Date:  2010-09-10       Impact factor: 3.445

Review 6.  Appendicitis in children less than five years old: A challenge for the general practitioner.

Authors:  Pierluigi Marzuillo; Claudio Germani; Baruch S Krauss; Egidio Barbi
Journal:  World J Clin Pediatr       Date:  2015-05-08

7.  Prospective evaluation of a clinical practice guideline for diagnosis of appendicitis in children.

Authors:  Genevieve Santillanes; Sonia Simms; Marianne Gausche-Hill; Michael Diament; Brant Putnam; Richard Renslo; Jumie Lee; Elga Tinger; Roger J Lewis
Journal:  Acad Emerg Med       Date:  2012-07-31       Impact factor: 3.451

8.  Application with repeated serum biomarkers in pediatric appendicitis in clinical surgery.

Authors:  Han-Ping Wu; Yun-Ching Fu
Journal:  Pediatr Surg Int       Date:  2009-11-18       Impact factor: 1.827

9.  Imaging of acute appendicitis in children: EU versus U.S. ... or US versus CT? A North American perspective.

Authors:  Donald P Frush; Karen S Frush; Keith T Oldham
Journal:  Pediatr Radiol       Date:  2009-02-17

10.  Appendectomy in the pediatric population-a German nationwide cohort analysis.

Authors:  Jan-Hendrik Gosemann; A Lange; J Zeidler; J Blaser; C Dingemann; B M Ure; M Lacher
Journal:  Langenbecks Arch Surg       Date:  2016-04-26       Impact factor: 3.445

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