Literature DB >> 14729361

Lens regeneration in mice: implications in cataracts.

Mindy K Call, Matthew W Grogg, Katia Del Rio-Tsonis, Panagiotis A Tsonis.   

Abstract

Lens regeneration in adult mice is possible when the lens capsule is left behind after lentectomy. The lens is regenerated by the remaining adherent lens epithelial cells, which differentiate to form lens fibres within days, showing normal morphology and bow regions. Epithelial to mesenchymal cell transformation is also seen during the early stages. The mouse, therefore, can become an indispensable animal model for cataract research, surgery and therapy.

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Year:  2004        PMID: 14729361     DOI: 10.1016/j.exer.2003.10.021

Source DB:  PubMed          Journal:  Exp Eye Res        ISSN: 0014-4835            Impact factor:   3.467


  25 in total

1.  Implication of the miR-184 and miR-204 competitive RNA network in control of mouse secondary cataract.

Authors:  Andrea Hoffmann; Yusen Huang; Rinako Suetsugu-Maki; Carol S Ringelberg; Craig R Tomlinson; Katia Del Rio-Tsonis; Panagiotis A Tsonis
Journal:  Mol Med       Date:  2012-05-09       Impact factor: 6.354

Review 2.  Eye on regeneration.

Authors:  Mindy K Call; Matthew W Grogg; Panagiotis A Tsonis
Journal:  Anat Rec B New Anat       Date:  2005-11

Review 3.  How to build and rebuild a lens.

Authors:  Panagiotis A Tsonis
Journal:  J Anat       Date:  2006-10       Impact factor: 2.610

4.  Fibronectin regulates growth factor signaling and cell differentiation in primary lens cells.

Authors:  Judy K VanSlyke; Bruce A Boswell; Linda S Musil
Journal:  J Cell Sci       Date:  2018-11-20       Impact factor: 5.285

Review 5.  Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract.

Authors:  F J Lovicu; E H Shin; J W McAvoy
Journal:  Exp Eye Res       Date:  2015-05-21       Impact factor: 3.467

Review 6.  Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape.

Authors:  J W McAvoy; L J Dawes; Y Sugiyama; F J Lovicu
Journal:  Exp Eye Res       Date:  2016-04-21       Impact factor: 3.467

7.  Aldose reductase inhibition enhances lens regeneration in mice.

Authors:  Leonid M Zukin; Michelle G Pedler; Kevin Chyung; Sarah Seiwald; Patricia Lenhart; Biehuoy Shieh; J Mark Petrash
Journal:  Chem Biol Interact       Date:  2019-04-23       Impact factor: 5.192

Review 8.  Diverse Evolutionary Origins and Mechanisms of Lens Regeneration.

Authors:  Jonathan J Henry; Paul W Hamilton
Journal:  Mol Biol Evol       Date:  2018-07-01       Impact factor: 16.240

9.  Expression of transcription factors and crystallin proteins during rat lens regeneration.

Authors:  Yusen Huang; Lixin Xie
Journal:  Mol Vis       Date:  2010-03-03       Impact factor: 2.367

10.  Intrinsic lens forming potential of mouse lens epithelial versus newt iris pigment epithelial cells in three-dimensional culture.

Authors:  Andrea Hoffmann; Kenta Nakamura; Panagiotis A Tsonis
Journal:  Tissue Eng Part C Methods       Date:  2013-07-10       Impact factor: 3.056

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