| Literature DB >> 14729326 |
Martin Cohen-Gonsaud1, Nicholas H Keep, Angharad P Davies, John Ward, Brian Henderson, Gilles Labesse.
Abstract
The novel bacterial cytokine family--resuscitation-promoting factors (Rpfs)--share a conserved domain of uncharacterized function. Predicting the structure of this domain suggests that Rpfs possess a lysozyme-like domain. The model highlights the good conservation of residues involved in catalysis and substrate binding. A lysozyme-like function makes sense for this domain in the light of experimental characterization of the biological function of Rpfs.Mesh:
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Year: 2004 PMID: 14729326 DOI: 10.1016/j.tibs.2003.10.009
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807