Literature DB >> 14728485

Building an application framework for integrative genomics.

Heta N Ray1, Vamsi K Mootha, Aziz A Boxwala.   

Abstract

The accelerated pace of biological research and the current availability of whole-genome data sets provides significant new sources of functional insight. We designed an architecture and framework for software to query and explore such data in an orderly and iterative fashion. The architecture is intended to provide an extensible platform for developing web based bioinformatics applications and to offer a flexible and end-user-extensible software environment to explore and integrate disparate biological data sources. This will enable the user to explore existing relationships and discover new functional relationships among these data.

Mesh:

Year:  2003        PMID: 14728485      PMCID: PMC1479937     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  1 in total

1.  Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics.

Authors:  Vamsi K Mootha; Pierre Lepage; Kathleen Miller; Jakob Bunkenborg; Michael Reich; Majbrit Hjerrild; Terrye Delmonte; Amelie Villeneuve; Robert Sladek; Fenghao Xu; Grant A Mitchell; Charles Morin; Matthias Mann; Thomas J Hudson; Brian Robinson; John D Rioux; Eric S Lander
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-14       Impact factor: 11.205

  1 in total
  1 in total

1.  Esrrb is a cell-cycle-dependent associated factor balancing pluripotency and XEN differentiation.

Authors:  Sapir Herchcovici Levy; Sharon Feldman Cohen; Lee Arnon; Shlomtzion Lahav; Muhammad Awawdy; Adi Alajem; Danny Bavli; Xue Sun; Yosef Buganim; Oren Ram
Journal:  Stem Cell Reports       Date:  2022-05-19       Impact factor: 7.294

  1 in total

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