Model-based design and implementation of secure, interoperable EHR systems.

For designing and implementing secure, interoperable, portable, and future-proof EHR systems, a comprehensive and standardized methodology supported by appropriate tools has to be established and applied. Based on the component paradigm, the ISO Reference Model - Open Distributed Processing has been used to describe the different views on information systems deploying the appropriate vocabulary for each single model view. The concepts considered rank from legal, organizational, and functional up to technical aspects of systems. The harmonization of vocabularies can be performed by meta-languages. The approach has been demonstrated for the model-based design, implementation and maintenance of a clinical study distributed over the Internet.