Literature DB >> 14726943

Developing meaningful cohorts for human exposure models.

Stephen E Graham1, Thomas McCurdy.   

Abstract

This paper summarizes numerous statistical analyses focused on the US Environmental Protection Agency's Consolidated Human Activity Database (CHAD), used by many exposure modelers as the basis for data on what people do and where they spend their time. In doing so, modelers tend to divide the total population being analyzed into "cohorts", to reduce extraneous interindividual variability by focusing on people with common characteristics. Age and gender are typically used as the primary cohort-defining attributes, but more complex exposure models also use weather, day-of-the-week, and employment attributes for this purpose. We analyzed all of these attributes and others to determine if statistically significant differences exist among them to warrant their being used to define distinct cohort groups. We focused our attention mostly on the relationship between cohort attributes and the time spent outdoors, indoors, and in motor vehicles. Our results indicate that besides age and gender, other important attributes for defining cohorts are the physical activity level of individuals, weather factors such as daily maximum temperature in combination with months of the year, and combined weekday/weekend with employment status. Less important are precipitation and ethnic data. While statistically significant, the collective set of attributes does not explain a large amount of variance in outdoor, indoor, or in-vehicle locational decisions. Based on other research, parameters such as lifestyle and life stages that are absent from CHAD might have reduced the amount of unexplained variance. At this time, we recommend that exposure modelers use age and gender as "first-order" attributes to define cohorts followed by physical activity level, daily maximum temperature or other suitable weather parameters, and day type possibly beyond a simple weekday/weekend classification.

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Year:  2004        PMID: 14726943     DOI: 10.1038/sj.jea.7500293

Source DB:  PubMed          Journal:  J Expo Anal Environ Epidemiol        ISSN: 1053-4245


  16 in total

1.  Source, Characterization of Indoor Dust PAHs and the Health Risk on Chinese Children.

Authors:  Xin-Qi Wang; Xu Li; Yu-Yan Yang; Lin Fan; Xu Han; Li Li; Hang Liu; Tan-Xi Ge; Li-Qin Su; Xian-Liang Wang; Yuan-Duo Zhu
Journal:  Curr Med Sci       Date:  2021-04-20

2.  Time-location patterns of a diverse population of older adults: the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air).

Authors:  Elizabeth W Spalt; Cynthia L Curl; Ryan W Allen; Martin Cohen; Sara D Adar; Karen H Stukovsky; Ed Avol; Cecilia Castro-Diehl; Cathy Nunn; Karen Mancera-Cuevas; Joel D Kaufman
Journal:  J Expo Sci Environ Epidemiol       Date:  2015-04-29       Impact factor: 5.563

3.  Factors influencing time-location patterns and their impact on estimates of exposure: the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air).

Authors:  Elizabeth W Spalt; Cynthia L Curl; Ryan W Allen; Martin Cohen; Kayleen Williams; Jana A Hirsch; Sara D Adar; Joel D Kaufman
Journal:  J Expo Sci Environ Epidemiol       Date:  2015-04-29       Impact factor: 5.563

4.  Time-location patterns of a population living in an air pollution hotspot.

Authors:  Xiangmei May Wu; Zhihua Tina Fan; Pamela Ohman-Strickland
Journal:  J Environ Public Health       Date:  2010-04-22

Review 5.  Exposure science: a view of the past and milestones for the future.

Authors:  Paul J Lioy
Journal:  Environ Health Perspect       Date:  2010-03-22       Impact factor: 9.031

6.  Mechanistic modeling of emergency events: assessing the impact of hypothetical releases of anthrax.

Authors:  S S Isukapalli; P J Lioy; P G Georgopoulos
Journal:  Risk Anal       Date:  2008-06       Impact factor: 4.000

7.  Characterizing the impact of projected changes in climate and air quality on human exposures to ozone.

Authors:  Kathie L Dionisio; Christopher G Nolte; Tanya L Spero; Stephen Graham; Nina Caraway; Kristen M Foley; Kristin K Isaacs
Journal:  J Expo Sci Environ Epidemiol       Date:  2017-01-25       Impact factor: 5.563

Review 8.  Global influenza seasonality: reconciling patterns across temperate and tropical regions.

Authors:  James Tamerius; Martha I Nelson; Steven Z Zhou; Cécile Viboud; Mark A Miller; Wladimir J Alonso
Journal:  Environ Health Perspect       Date:  2010-11-19       Impact factor: 9.031

9.  Longitudinal variability of time-location/activity patterns of population at different ages: a longitudinal study in California.

Authors:  Xiangmei Wu; Deborah H Bennett; Kiyoung Lee; Diana L Cassady; Beate Ritz; Irva Hertz-Picciotto
Journal:  Environ Health       Date:  2011-09-20       Impact factor: 5.984

10.  A nice day for an infection? Weather conditions and social contact patterns relevant to influenza transmission.

Authors:  Lander Willem; Kim Van Kerckhove; Dennis L Chao; Niel Hens; Philippe Beutels
Journal:  PLoS One       Date:  2012-11-14       Impact factor: 3.240

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