Literature DB >> 1472635

The nuclear autoimmune antigen Ku is also present on the cell surface.

R G Dalziel1, S C Mendelson, J P Quinn.   

Abstract

Polyclonal antibodies were raised against the individual 85 and 70 kDa subunits of the Ku complex purified from nuclear extract prepared from the T cell line MLA144. They specifically recognise the appropriate subunits of the Ku complex from whole cell extract of HeLa cells using Western blot analysis. They are also able to identify the Ku proteins present in the cell membrane using FACS analysis.

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Year:  1992        PMID： 1472635     DOI： 10.3109/08916939209112334

Source DB:  PubMed          Journal:  Autoimmunity        ISSN： 0891-6934            Impact factor:   2.815


  8 in total

1.  Up-regulation of the Ku heterodimer in Drosophila testicular cyst cells.

Authors:  Alexander M Boutanaev; Lyudmila M Mikhaylova; Dmitry I Nurminsky
Journal:  FEBS Lett       Date:  2007-03-30       Impact factor: 4.124

2.  Preclinical evaluation of (111)In-DTPA-INCA-X anti-Ku70/Ku80 monoclonal antibody in prostate cancer.

Authors:  Susan Evans-Axelsson; Oskar Vilhelmsson Timmermand; Charlotte Welinder; Carl Ak Borrebaeck; Sven-Erik Strand; Thuy A Tran; Bo Jansson; Anders Bjartell
Journal:  Am J Nucl Med Mol Imaging       Date:  2014-06-07

3.  Ku-related antigens are associated with transcriptionally active loci in Chironomus polytene chromosomes.

Authors:  E Gorab; L M Botella; J P Quinn; J M Amabis; J L Díez
Journal:  Chromosoma       Date:  1996-09       Impact factor: 4.316

4.  The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9.

Authors:  Sylvie Monferran; Jenny Paupert; Stéphanie Dauvillier; Bernard Salles; Catherine Muller
Journal:  EMBO J       Date:  2004-09-23       Impact factor: 11.598

5.  Distribution, cellular localization, and therapeutic potential of the tumor-associated antigen Ku70/80 in glioblastoma multiforme.

Authors:  Oscar Persson; Leif G Salford; Johan Fransson; Bengt Widegren; Carl A K Borrebaeck; Bo Holmqvist
Journal:  J Neurooncol       Date:  2009-10-07       Impact factor: 4.130

6.  Ku protein levels, localization and association to replication origins in different stages of breast tumor progression.

Authors:  Khalil Abdelbaqi; Domenic Di Paola; Emmanouil Rampakakis; Maria Zannis-Hadjopoulos
Journal:  J Cancer       Date:  2013-05-26       Impact factor: 4.207

7.  Ku86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells.

Authors:  Charles A Gullo; Feng Ge; Geraline Cow; Gerrard Teoh
Journal:  Cancer Cell Int       Date:  2008-04-29       Impact factor: 5.722

8.  Selective Targeting to Glioma with Nucleic Acid Aptamers.

Authors:  Shraddha Aptekar; Mohit Arora; Clare Louise Lawrence; Robert William Lea; Katherine Ashton; Tim Dawson; Jane Elizabeth Alder; Lisa Shaw
Journal:  PLoS One       Date:  2015-08-07       Impact factor: 3.240
  8 in total

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