Literature DB >> 14726118

New screening method for the determination of stability of pharmaceuticals.

Peter Simon1, Miroslav Veverka, Jozef Okuliar.   

Abstract

A rapid method for obtaining the parameters describing the lengths of oxidation induction periods from non-isothermal differential scanning calorimetry measurements, based on the dependence of onset temperature of the oxidation peak on heating rate, is presented. The method has been applied for screening the stability of a set of three pharmaceuticals. The order of stabilities of the compounds obtained by the method coincides with the order determined by classical stability tests.

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Year:  2004        PMID: 14726118     DOI: 10.1016/j.ijpharm.2003.10.003

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  3 in total

1.  Discovery pharmaceutics--challenges and opportunities.

Authors:  Xue-Qing Chen; Melissa D Antman; Christoph Gesenberg; Olafur S Gudmundsson
Journal:  AAPS J       Date:  2006-06-02       Impact factor: 4.009

2.  Use of 2,2'-azobis(2-amidinopropane) dihydrochloride as a reagent tool for evaluation of oxidative stability of drugs.

Authors:  Seema Betigeri; Ajit Thakur; Krishnaswamy Raghavan
Journal:  Pharm Res       Date:  2005-02       Impact factor: 4.200

3.  The Analysis of the Physicochemical Properties of Benzocaine Polymorphs.

Authors:  Magdalena Paczkowska; Gabriela Wiergowska; Andrzej Miklaszewski; Anna Krause; Magdalena Mroczkowka; Przemysław Zalewski; Judyta Cielecka-Piontek
Journal:  Molecules       Date:  2018-07-16       Impact factor: 4.411

  3 in total

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