Literature DB >> 14723515

The first total synthesis of 15-deoxy-Delta12,14-prostaglandin J2 and the unambiguous assignment of the C14 stereochemistry.

Kay M Brummond1, Peter C Sill, Hongfeng Chen.   

Abstract

[reaction: see text] The first total synthesis of 15-deoxy-Delta12,14-prostaglandin J2 is reported. The highly unsaturated cyclopentenone prostaglandin was obtained via a silicon-tethered allenic [2 + 2 + 1] cycloaddition reaction developed in our group. In addition, the stereochemistry at C14 has been assigned unambiguously.

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Year:  2004        PMID： 14723515     DOI： 10.1021/ol035590v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

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Authors:  William B Reid; Jesse R McAtee; Donald A Watson
Journal:  Organometallics       Date:  2019-09-26       Impact factor: 3.876

2.  15d-Prostaglandin J2 induced reactive oxygen species-mediated apoptosis during experimental visceral leishmaniasis.

Authors:  Preeti Vishwakarma; Naveen Parmar; Pawan Kumar Yadav; Pragya Chandrakar; Susanta Kar
Journal:  J Mol Med (Berl)       Date:  2016-02-01       Impact factor: 4.599

3.  Identification of chromomoric acid C-I as an Nrf2 activator in Chromolaena odorata.

Authors:  Elke H Heiss; Thi Van Anh Tran; Kristin Zimmermann; Stefan Schwaiger; Corina Vouk; Barbara Mayerhofer; Clemens Malainer; Atanas G Atanasov; Hermann Stuppner; Verena M Dirsch
Journal:  J Nat Prod       Date:  2014-01-29       Impact factor: 4.050
  3 in total

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