Production of transglutaminase from Bacillus circulans on solid-state and submerged cultivations.

A Bacillus circulans strain, isolated in the Amazon basin, produced a transglutaminase (EC 2.3 x 2.13) in both submerged and solid-state cultivation. Enzyme activity in the former case reached 0.69 U ml(-1) after 160 h cultivation on starch based medium, and in the latter 0.61 U ml(-1) after 60 h cultivation on soybean industrial fibrous residue, a non-expensive agro-industrial residue.