Literature DB >> 14714970

Intractable skin necrosis and interstitial pneumonia in amyopathic dermatomyositis, successfully treated with cyclosporin A.

Yasuhiro Shimojima1, Wataru Ishii, Takashi Kato, Kenichi Hoshi, Masayuki Matsuda, Takao Hashimoto, Yukio Tanaka, Shu-ichi Ikeda.   

Abstract

We report a patient with amyopathic dermatomyositis (DM) who mainly showed interstitial pneumonia and intractable skin necrosis in bilateral elbows and soles with a poor response to immunomediated therapy, including corticosteroid and high-dose intravenous immunoglobulin. Soon after starting oral cyclosporin A (CyA) the skin lesions healed completely and the interstitial pneumonia promptly improved in parallel with a decrease in serum KL-6. Since fatal interstitial pneumonia is frequently associated with amyopathic DM as in this case, administration of CyA should be actively considered as a therapeutic option when clinical symtoms are progressive and resistant to conventional treatments.

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Year:  2003        PMID： 14714970     DOI： 10.2169/internalmedicine.42.1253

Source DB:  PubMed          Journal:  Intern Med        ISSN： 0918-2918            Impact factor:   1.271


  8 in total

1.  The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): a retrospective study.

Authors:  David Fiorentino; Lorinda Chung; Jeff Zwerner; Antony Rosen; Livia Casciola-Rosen
Journal:  J Am Acad Dermatol       Date:  2011-04-29       Impact factor: 11.527

Review 2.  Beneficial effect of treatment with cyclosporin A in a case of refractory antisynthetase syndrome.

Authors:  Magdalena Jankowska; Barbara Butto; Alicja Debska-Slizień; Bolesław Rutkowski
Journal:  Rheumatol Int       Date:  2007-01-13       Impact factor: 3.580

3.  Coadministration of cyclosporin a with prednisolone in acute interstitial pneumonia complicating polymyositis/dermatomyositis.

Authors:  Yasuhiro Shimojima; Wataru Ishii; Masayuki Matsuda; Nagaaki Katoh; Ko-Ichi Tazawa; Yoshiki Sekijima; Shu-Ichi Ikeda
Journal:  Clin Med Insights Arthritis Musculoskelet Disord       Date:  2012-03-14

4.  Successful treatment with tacrolimus of progressive interstitial pneumonia associated with amyopathic dermatomyositis refractory to cyclosporine.

Authors:  Masaru Ando; Eishi Miyazaki; Mari Yamasue; Yukiko Sadamura; Toshihiro Ishii; Ryuichi Takenaka; Takeo Ito; Shin-ichi Nureki; Toshihide Kumamoto
Journal:  Clin Rheumatol       Date:  2010-02-04       Impact factor: 3.650

Review 5.  Covert clues: the non-hallmark cutaneous manifestations of dermatomyositis.

Authors:  Rochelle L Castillo; Alisa N Femia
Journal:  Ann Transl Med       Date:  2021-03

6.  Coadministration of tacrolimus with corticosteroid accelerates recovery in refractory patients with polymyositis/ dermatomyositis: a retrospective study.

Authors:  Yasuhiro Shimojima; Wataru Ishii; Masayuki Matsuda; Ko-ichi Tazawa; Shu-ichi Ikeda
Journal:  BMC Musculoskelet Disord       Date:  2012-11-22       Impact factor: 2.362

7.  Intravenous Immune Globulin in Amyopathic Dermatomyositis - Report of Two Cases and Review of the Literature.

Authors:  John M Cafardi; Naveed Sami
Journal:  Open Rheumatol J       Date:  2015-11-04

Review 8.  Protein-losing Gastroenteropathy Related to Mixed Connective Tissue Disease: A Case Report of a Successful Outcome and Literature Review.

Authors:  Yuya Kobayashi; Yasuhiro Shimojima; Yasufumi Kondo; Ryota Takamatsu; Daigo Miyazaki; Dai Kishida; Yoshiki Sekijima; Shu-Ichi Ikeda
Journal:  Intern Med       Date:  2017-08-01       Impact factor: 1.271
  8 in total

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