UNLABELLED: BACKGROUND There are few long-term follow-up data on the relation between body mass index (BMI) in adolescence and in adulthood, and between adolescent BMI and adult mortality. The present study explores these relations. METHODS: In Norwegian health surveys during 1963-1999, height and weight were measured for 128,121 persons in a standardized way both in adolescence (age 14-19 years) and 10 or more years later. Persons were followed for an average of 9.7 years after the adult measurement. Cox proportional hazard regression models were used to study the association between adolescent and adult BMI and mortality. RESULTS: The odds ratio of obesity (BMI >/=30) in adulthood increased steadily with BMI in adolescence, from 0.2 for low BMI up to 16 for very high BMI. Very high adolescent BMI was associated with 30-40% higher adult mortality compared with medium BMI. Adjusting for adult BMI explained most of the association of adolescent obesity and mortality, especially among men. Adjustment for smoking did not change the results. CONCLUSIONS: Obesity in adolescence tends to persist into adulthood. Adolescent obesity is also connected to excess mortality, but this excess seems to be explained mostly by obesity in adulthood. High BMI in adolescence seems to be predictive of both adult obesity and mortality.
UNLABELLED: BACKGROUND There are few long-term follow-up data on the relation between body mass index (BMI) in adolescence and in adulthood, and between adolescent BMI and adult mortality. The present study explores these relations. METHODS: In Norwegian health surveys during 1963-1999, height and weight were measured for 128,121 persons in a standardized way both in adolescence (age 14-19 years) and 10 or more years later. Persons were followed for an average of 9.7 years after the adult measurement. Cox proportional hazard regression models were used to study the association between adolescent and adult BMI and mortality. RESULTS: The odds ratio of obesity (BMI >/=30) in adulthood increased steadily with BMI in adolescence, from 0.2 for low BMI up to 16 for very high BMI. Very high adolescent BMI was associated with 30-40% higher adult mortality compared with medium BMI. Adjusting for adult BMI explained most of the association of adolescent obesity and mortality, especially among men. Adjustment for smoking did not change the results. CONCLUSIONS:Obesity in adolescence tends to persist into adulthood. Adolescent obesity is also connected to excess mortality, but this excess seems to be explained mostly by obesity in adulthood. High BMI in adolescence seems to be predictive of both adult obesity and mortality.
Authors: Sofia Ramalho; Pedro F Saint-Maurice; Diana Silva; Helena Ferreira Mansilha; Cátia Silva; Sónia Gonçalves; Paulo Machado; Eva Conceição Journal: Eat Weight Disord Date: 2018-12-05 Impact factor: 4.652
Authors: Kevin W Ryan; Paula Card-Higginson; Jennifer L Shaw; Sarah A Ganahl; Joseph W Thompson Journal: Public Health Rep Date: 2007 May-Jun Impact factor: 2.792
Authors: Kenneth F Adams; Michael F Leitzmann; Rachel Ballard-Barbash; Demetrius Albanes; Tamara B Harris; Albert Hollenbeck; Victor Kipnis Journal: Am J Epidemiol Date: 2013-10-29 Impact factor: 4.897
Authors: Kelly A Hirko; Elizabeth D Kantor; Sarah S Cohen; William J Blot; Meir J Stampfer; Lisa B Signorello Journal: Am J Epidemiol Date: 2015-05-13 Impact factor: 4.897
Authors: May A Beydoun; J Atilio Canas; Hind A Beydoun; Xiaoli Chen; Monal R Shroff; Alan B Zonderman Journal: J Nutr Date: 2012-07-18 Impact factor: 4.798
Authors: Arash Etemadi; Christian C Abnet; Farin Kamangar; Farhad Islami; Hooman Khademi; Akram Pourshams; Hossein Poustchi; Mohammad Bagheri; Amir Ali Sohrabpour; Ali Aliasgar; Masoud Khoshnia; Sholom Wacholder; Charles C Matthews; Paul D Pharoah; Paul Brennan; Paolo Boffetta; Reza Malekzadeh; Sanford M Dawsey Journal: Eur J Epidemiol Date: 2014-02-21 Impact factor: 8.082