Literature DB >> 14712032

(Z)-2-(1H-Indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one.

Vijayakumar N Sonar1, Sean Parkin, Peter A Crooks.   

Abstract

The title compound, C(16)H(16)N(2)O, which contains a double bond connecting an azabicyclic ring system to an indol-3-ylmethylene group, crystallizes from a solution in ethyl acetate. The geometries of the two crystallographically independent molecules are nearly identical. The crystal packing of the title compound involves two types of intermolecular hydrogen bond.

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Year:  2003        PMID: 14712032     DOI: 10.1107/s0108270103026076

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN: 0108-2701            Impact factor:   1.172


  1 in total

1.  Novel substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(+/-)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents.

Authors:  Vijayakumar N Sonar; Y Thirupathi Reddy; Konjeti R Sekhar; Soumya Sasi; Michael L Freeman; Peter A Crooks
Journal:  Bioorg Med Chem Lett       Date:  2007-10-17       Impact factor: 2.823

  1 in total

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