Literature DB >> 1471160

Isolation and structure determination of natural analogues of the mycotoxin ochratoxin A produced by Aspergillus ochraceus.

R Hadidane1, H Bacha, E E Creppy, M Hammami, F Ellouze, G Dirheimer.   

Abstract

Three new natural mycotoxins, analogues of ochratoxin A, in which the phenylalanine moiety is replaced by serine, hydroxyproline or lysine, were isolated from cultures of Aspergillus ochraceus by TLC followed by HPLC column chromatography. Their structures were determined after acidic hydrolysis by the characterisation of both their amino acid moieties and of ochratoxin alpha, the chlorinated dihydroisocoumarin moiety of ochratoxin A. These structures were confirmed by mass spectrum analysis.

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Year:  1992        PMID： 1471160     DOI： 10.1016/0300-483x(92)90192-h

Source DB:  PubMed          Journal:  Toxicology        ISSN： 0300-483X            Impact factor:   4.221


  6 in total

1.  Detoxification of ochratoxin A, a food contaminant: Prevention of growth of Aspergillus ochraceus and its production of ochratoxin A.

Authors:  P Deberghes; A M Betbeder; F Boisard; R Blanc; J F Delaby; S Krivobok; R Steiman; F Seigle-Murandi; E Creppy
Journal:  Mycotoxin Res       Date:  1995-03       Impact factor: 3.833

2.  Sister chromatid exchange frequency in cultured isolated porcine urinary bladder epithelial cells (PUBEC) treated with ochratoxin A and alpha.

Authors:  W Föllmann; I E Hillebrand; E E Creppy; H M Bolt
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

3.  Ochratoxin-A production in Brazilian dry beans (Phaseolus vulgaris L.).

Authors:  M S Cordeiro; J Amaya-Farfan; P J Moran
Journal:  Mycotoxin Res       Date:  1995-03       Impact factor: 3.833

4.  Foodstuffs and human blood contamination by the mycotoxin ochratoxin A: correlation with chronic interstitial nephropathy in Tunisia.

Authors:  K Maaroufi; A Achour; A M Betbeder; M Hammami; F Ellouz; E E Creppy; H Bacha
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

5.  Bacillus subtilis ANSB168 Producing d-alanyl-d-alanine Carboxypeptidase Could Alleviate the Immune Injury and Inflammation Induced by Ochratoxin A.

Authors:  Hanrui Qing; Xueting Huo; Shimeng Huang; Lihong Zhao; Jianyun Zhang; Cheng Ji; Qiugang Ma
Journal:  Int J Mol Sci       Date:  2021-11-08       Impact factor: 5.923

Review 6.  Aspergillus ochraceus: Metabolites, Bioactivities, Biosynthesis, and Biotechnological Potential.

Authors:  Rawan H Hareeri; Mohammed M Aldurdunji; Hossam M Abdallah; Ali A Alqarni; Shaimaa G A Mohamed; Gamal A Mohamed; Sabrin R M Ibrahim
Journal:  Molecules       Date:  2022-10-10       Impact factor: 4.927
  6 in total

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