| Literature DB >> 14711432 |
Abstract
The discovery of Sfi1p as a novel binding partner for the Ca2+-binding protein centrin has provided new insight into the dynamic behavior of centrosomes. Sfi1 binds to multiple centrin molecules along a series of internal repeats, and the complex forms Ca2+-sensitive contractile fibers that function to reorient centrioles and alter centrosome structure.Entities:
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Year: 2004 PMID： 14711432 DOI： 10.1016/j.cub.2003.12.019
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834