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Literature DB >> 14710349

Caloric restriction and insulin-like growth factors in aging and cancer.

Abstract

This review examines the influence of a reduction in caloric intake on cancer and longevity. Data indicating that rodents subjected to caloric restriction display lower tumor incidence, reduced susceptibility to carcinogens and extended lifespan is analyzed. The potential role of the growth hormone/insulin-like growth factor type 1 (IGF-I) axis in this effect is discussed as is the evidence that a reduction in growth hormone and/or IGF-I leads to a reduction in spontaneous tumors and susceptibility to carcinogens.

Entities: Disease Gene

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Year: 2003 PMID： 14710349 DOI： 10.1055/s-2004-814156

Source DB: PubMed Journal: Horm Metab Res ISSN： 0018-5043 Impact factor: 2.936

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Cited

13 in total

1. Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT.

Authors: Cesar L Moreno; Michelle E Ehrlich; Charles V Mobbs
Journal: Neurobiol Dis Date: 2015-10-17 Impact factor: 5.996

Review 2. Dietary factors, hormesis and health.

Authors: Mark P Mattson
Journal: Ageing Res Rev Date: 2007-09-01 Impact factor: 10.895

Review 3. Role of the hypothalamus in mediating protective effects of dietary restriction during aging.

Authors: Penny A Dacks; Cesar L Moreno; Esther S Kim; Bridget K Marcellino; Charles V Mobbs
Journal: Front Neuroendocrinol Date: 2012-12-20 Impact factor: 8.606

Review 4. NRF2, cancer and calorie restriction.

Authors: A Martín-Montalvo; J M Villalba; P Navas; R de Cabo
Journal: Oncogene Date: 2010-11-08 Impact factor: 9.867

5. Metabolic adaptations to short-term every-other-day feeding in long-living Ames dwarf mice.

Authors: Holly M Brown-Borg; Sharlene Rakoczy
Journal: Exp Gerontol Date: 2013-07-04 Impact factor: 4.032

6. Antiproliferative effects of PACAP and VIP in serum-starved glioma cells.

Authors: Agata Grazia D'Amico; Soraya Scuderi; Salvatore Saccone; Alessandro Castorina; Filippo Drago; Velia D'Agata
Journal: J Mol Neurosci Date: 2013-07-31 Impact factor: 3.444

7. Transcriptome analysis of age-, gender- and diet-associated changes in murine thymus.

Authors: Ana Lustig; Ashani T Weeraratna; William W Wood; Diane Teichberg; Dorothy Bertak; Arnell Carter; Suresh Poosala; Jeffrey Firman; Kevin G Becker; Alan B Zonderman; Dan L Longo; Dennis D Taub
Journal: Cell Immunol Date: 2007-05-17 Impact factor: 4.868