| Literature DB >> 14709883 |
Momoyo Ichimaru1, Noriyoshi Nakatani, Tomoko Takahashi, Yumi Nishiyama, Masataka Moriyasu, Atsushi Kato, Simon G Mathenge, Francis D Juma, Joseph N Nganga.
Abstract
Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), isouvaretin (5), diuvaretin (6), and uvangoletin (7). The structural elucidation of compounds 1 and 2 in spectroscopic studies is described. C-Benzylated dihydrochalcones, especially 1, 2, 4, and 6, showed considerable cytotoxicity toward human promyelocytic leukemia HL-60 cells.Entities:
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Year: 2004 PMID： 14709883 DOI： 10.1248/cpb.52.138
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645