Literature DB >> 14708926

An approach to dyspnea in advanced disease.

Romayne Gallagher1.   

Abstract

INTRODUCTION: To describe an approach to assessment and treatment of dyspnea. SOURCES OF INFORMATION: New level I evidence can guide management of dyspnea in advanced illness. Assessment and use of adjuvant medications and oxygen relies on level II and III evidence. MAIN MESSAGE: Opioids are first-line therapy for managing dyspnea in advanced illness. They are safe and effective in reducing shortness of breath. Neuroleptics are useful adjuvant medications. Evidence does not support use of oxygen for every patient experiencing dyspnea; it should be tried for patients who do not benefit from first-line medications and nonmedicinal therapies.
CONCLUSION: Opioids relieve dyspnea and are indicated as first-line treatment for dyspnea arising from advanced disease of any cause.

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Year:  2003        PMID: 14708926      PMCID: PMC2214160     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  24 in total

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Journal:  Br J Clin Pharmacol       Date:  1985-06       Impact factor: 4.335

9.  Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea.

Authors:  Amy P Abernethy; David C Currow; Peter Frith; Belinda S Fazekas; Annie McHugh; Chuong Bui
Journal:  BMJ       Date:  2003-09-06

10.  Factors correlated with dyspnea in advanced lung cancer patients: organic causes and what else?

Authors:  Keiko Tanaka; Tatsuo Akechi; Toru Okuyama; Yutaka Nishiwaki; Yosuke Uchitomi
Journal:  J Pain Symptom Manage       Date:  2002-06       Impact factor: 3.612

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  1 in total

1.  Opioid-induced neurotoxicity.

Authors:  Romayne Gallagher
Journal:  Can Fam Physician       Date:  2007-03       Impact factor: 3.275

  1 in total

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