Literature DB >> 14708578

A survey of codon and amino acid frequency bias in microbial genomes focusing on translational efficiency.

Rainer Merkl1.   

Abstract

Unequal use of synonymous codons has been found in several prokaryotic and eukaryotic genomes. This bias has been associated with translational efficiency. The prevalence of this bias across lineages is currently unknown. Here, a new method (GCB) to measure codon usage bias is presented. It uses an iterative approach for the determination of codon scores and allows the computation of an index of codon bias suitable for interspecies comparison. A server to calculate GCB-values of individual genes as well as a list of compiled results are available at www.g21.bio.uni-goettingen.de. The method was applied to complete bacterial genomes. The relation of codon usage bias with amino acid composition and the choice of stop codons were determined and discussed.

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Year:  2003        PMID: 14708578     DOI: 10.1007/s00239-003-2499-1

Source DB:  PubMed          Journal:  J Mol Evol        ISSN: 0022-2844            Impact factor:   2.395


  34 in total

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Journal:  Nucleic Acids Res       Date:  1995-02-25       Impact factor: 16.971

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Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

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Journal:  Nucleic Acids Res       Date:  1987-02-11       Impact factor: 16.971

6.  A direct estimation of the context effect on the efficiency of termination.

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Journal:  J Mol Biol       Date:  1998-12-04       Impact factor: 5.469

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Journal:  Mol Biol Evol       Date:  1994-03       Impact factor: 16.240

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Authors:  S Karlin; J Mrázek; A M Campbell
Journal:  Mol Microbiol       Date:  1998-09       Impact factor: 3.501

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Journal:  Gene       Date:  1994-02-11       Impact factor: 3.688

Review 10.  Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes.

Authors:  H Grosjean; W Fiers
Journal:  Gene       Date:  1982-06       Impact factor: 3.688

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  12 in total

1.  Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models.

Authors:  Stephan Waack; Oliver Keller; Roman Asper; Thomas Brodag; Carsten Damm; Wolfgang Florian Fricke; Katharina Surovcik; Peter Meinicke; Rainer Merkl
Journal:  BMC Bioinformatics       Date:  2006-03-16       Impact factor: 3.169

2.  Alternative splicing acting as a bridge in evolution.

Authors:  Kemin Zhou; Asaf Salamov; Alan Kuo; Andrea L Aerts; Xiangyang Kong; Igor V Grigoriev
Journal:  Stem Cell Investig       Date:  2015-10-30

3.  Interspecific and intragenic differences in codon usage bias among vertebrate myosin heavy-chain genes.

Authors:  Mikio C Aoi; Bryan C Rourke
Journal:  J Mol Evol       Date:  2011-09-14       Impact factor: 2.395

4.  Synonymous codon usage bias dependent on local nucleotide context in the class Deinococci.

Authors:  Robert W Cutler; Panuwan Chantawannakul
Journal:  J Mol Evol       Date:  2008-08-12       Impact factor: 2.395

5.  Multilocus patterns of polymorphism and selection across the X chromosome of Caenorhabditis remanei.

Authors:  Asher D Cutter
Journal:  Genetics       Date:  2008-02-03       Impact factor: 4.562

6.  The effect of local nucleotides on synonymous codon usage in the honeybee (Apis mellifera L.) genome.

Authors:  Robert W Cutler; Panuwan Chantawannakul
Journal:  J Mol Evol       Date:  2007-05-29       Impact factor: 2.395

7.  MGC: a metagenomic gene caller.

Authors:  Achraf El Allali; John R Rose
Journal:  BMC Bioinformatics       Date:  2013-06-28       Impact factor: 3.169

8.  Quantification of codon selection for comparative bacterial genomics.

Authors:  Adam C Retchless; Jeffrey G Lawrence
Journal:  BMC Genomics       Date:  2011-07-25       Impact factor: 3.969

9.  Genes optimized by evolution for accurate and fast translation encode in Archaea and Bacteria a broad and characteristic spectrum of protein functions.

Authors:  Conrad von Mandach; Rainer Merkl
Journal:  BMC Genomics       Date:  2010-11-04       Impact factor: 3.969

10.  Predicting gene expression level from relative codon usage bias: an application to Escherichia coli genome.

Authors:  Uttam Roymondal; Shibsankar Das; Satyabrata Sahoo
Journal:  DNA Res       Date:  2009-01-08       Impact factor: 4.458

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