Literature DB >> 14708008

Regulation of the c-Abl and Bcr-Abl tyrosine kinases.

Oliver Hantschel1, Giulio Superti-Furga.   

Abstract

The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes. Its oncogenic counterpart, the Bcr-Abl fusion protein, causes certain human leukaemias. Recent insights into the structure and regulation of the c-Abl and Bcr-Abl tyrosine kinases have changed the way we look at these enzymes.

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Year:  2004        PMID： 14708008     DOI： 10.1038/nrm1280

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  182 in total

1.  A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation.

Authors:  Shuling Guo; Gregory Z Ferl; Rajendar Deora; Mireille Riedinger; Sheng Yin; James L Kerwin; Joseph A Loo; Owen N Witte
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-16       Impact factor: 11.205

2.  p185(BCR/ABL) has a lower sensitivity than p210(BCR/ABL) to the allosteric inhibitor GNF-2 in Philadelphia chromosome-positive acute lymphatic leukemia.

Authors:  Afsar A Mian; Anna Metodieva; Yousef Najajreh; Oliver G Ottmann; Jamal Mahajna; Martin Ruthardt
Journal:  Haematologica       Date:  2011-11-04       Impact factor: 9.941

3.  Proteome-wide detection of Abl1 SH3-binding peptides by integrating computational prediction and peptide microarray.

Authors:  Zheng Xu; Tingjun Hou; Nan Li; Yang Xu; Wei Wang
Journal:  Mol Cell Proteomics       Date:  2011-10-24       Impact factor: 5.911

4.  Allosteric BCR-ABL inhibitors in Philadelphia chromosome-positive acute lymphoblastic leukemia: novel opportunities for drug combinations to overcome resistance.

Authors:  Oliver Hantschel
Journal:  Haematologica       Date:  2012-02       Impact factor: 9.941

5.  The c-Abl expression in uterine epithelium during the mouse estrus cycle.

Authors:  A Yaba Ucar; U A Kayisli; N Demir
Journal:  J Mol Histol       Date:  2011-12-06       Impact factor: 2.611

6.  Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner.

Authors:  Teodora Pene-Dumitrescu; Thomas E Smithgall
Journal:  J Biol Chem       Date:  2010-05-07       Impact factor: 5.157

7.  c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression.

Authors:  Hui-Yi Kua; Huijuan Liu; Wai Fook Leong; Lili Li; Deyong Jia; Gang Ma; Yuanyu Hu; Xueying Wang; Jenny F L Chau; Ye-Guang Chen; Yuji Mishina; Sharon Boast; James Yeh; Li Xia; Guo-Qiang Chen; Lin He; Stephen P Goff; Baojie Li
Journal:  Nat Cell Biol       Date:  2012-06-24       Impact factor: 28.824

8.  Abl regulates smooth muscle cell proliferation by modulating actin dynamics and ERK1/2 activation.

Authors:  Li Jia; Ruping Wang; Dale D Tang
Journal:  Am J Physiol Cell Physiol       Date:  2012-02-01       Impact factor: 4.249

9.  Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype.

Authors:  Susan R Mallery; Daren Wang; Brian Santiago; Ping Pei; Steven P Schwendeman; Kari Nieto; Richard Spinney; Meng Tong; George Koutras; Brian Han; Andrew Holpuch; James Lang
Journal:  Cancer Prev Res (Phila)       Date:  2016-10-18

Review 10.  Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).

Authors:  Pengfei Xu; Chiara Ianes; Fabian Gärtner; Congxing Liu; Timo Burster; Vasiliy Bakulev; Najma Rachidi; Uwe Knippschild; Joachim Bischof
Journal:  Gene       Date:  2019-07-31       Impact factor: 3.688
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