Literature DB >> 14704205

A Sod2 null mutation confers severely reduced adult life span in Drosophila.

Atanu Duttaroy1, Anirban Paul, Mukta Kundu, Amy Belton.   

Abstract

A null mutation for the Sod2 gene, Sod2n283, was obtained in Drosophila melanogaster. Homozygous Sod2 null (Sodn283/Sodn283) adult flies survive up to 24 hr following eclosion, a phenotype reminiscent of mice, where Sod2-/- progeny suffer neonatal lethality. Sodn283/+ heterozygotes are sensitive to oxidative stress induced by paraquat treatment.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14704205      PMCID： PMC1462872     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  14 in total

1.  Overexpression of Mn-containing superoxide dismutase in transgenic Drosophila melanogaster.

Authors:  R J Mockett; W C Orr; J J Rahmandar; J J Benes; S N Radyuk; V I Klichko; R S Sohal
Journal:  Arch Biochem Biophys       Date:  1999-11-15       Impact factor: 4.013

2.  A stable genomic source of P element transposase in Drosophila melanogaster.

Authors:  H M Robertson; C R Preston; R W Phillis; D M Johnson-Schlitz; W K Benz; W R Engels
Journal:  Genetics       Date:  1988-03       Impact factor: 4.562

3.  Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis.

Authors:  J E Kokoszka; P Coskun; L A Esposito; D C Wallace
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

4.  Null mutation of copper/zinc superoxide dismutase in Drosophila confers hypersensitivity to paraquat and reduced longevity.

Authors:  J P Phillips; S D Campbell; D Michaud; M Charbonneau; A J Hilliker
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

5.  RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress.

Authors:  Kim Kirby; Jianguo Hu; Arthur J Hilliker; John P Phillips
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-27       Impact factor: 11.205

6.  Cu, Zn superoxide dismutase deficiency accelerates the time course of an age-related marker in Drosophila melanogaster.

Authors:  B Rogina; S L Helfand
Journal:  Biogerontology       Date:  2000       Impact factor: 4.277

7.  A P element containing suppressor of hairy-wing binding regions has novel properties for mutagenesis in Drosophila melanogaster.

Authors:  R R Roseman; E A Johnson; C K Rodesch; M Bjerke; R N Nagoshi; P K Geyer
Journal:  Genetics       Date:  1995-11       Impact factor: 4.562

8.  Mitochondrial disease in superoxide dismutase 2 mutant mice.

Authors:  S Melov; P Coskun; M Patel; R Tuinstra; B Cottrell; A S Jun; T H Zastawny; M Dizdaroglu; S I Goodman; T T Huang; H Miziorko; C J Epstein; D C Wallace
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-02       Impact factor: 11.205

9.  Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium.

Authors:  J P Phillips; J A Tainer; E D Getzoff; G L Boulianne; K Kirby; A J Hilliker
Journal:  Proc Natl Acad Sci U S A       Date:  1995-09-12       Impact factor: 11.205

10.  Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase.

Authors:  Y Li; T T Huang; E J Carlson; S Melov; P C Ursell; J L Olson; L J Noble; M P Yoshimura; C Berger; P H Chan; D C Wallace; C J Epstein
Journal:  Nat Genet       Date:  1995-12       Impact factor: 38.330
View more
  70 in total

1.  Superoxide Dismutase 2 is dispensable for platelet function.

Authors:  Trevor P Fidler; Jesse W Rowley; Claudia Araujo; Luc H Boudreau; Alex Marti; Rhonda Souvenir; Kali Dale; Eric Boilard; Andrew S Weyrich; E Dale Abel
Journal:  Thromb Haemost       Date:  2017-08-03       Impact factor: 5.249

Review 2.  Manganese superoxide dismutase: beyond life and death.

Authors:  Aaron K Holley; Sanjit Kumar Dhar; Yong Xu; Daret K St Clair
Journal:  Amino Acids       Date:  2010-05-08       Impact factor: 3.520

3.  The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old.

Authors:  Mette Soerensen; Kaare Christensen; Tinna Stevnsner; Lene Christiansen
Journal:  Mech Ageing Dev       Date:  2009-02-05       Impact factor: 5.432

4.  A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila.

Authors:  Alysia Vrailas-Mortimer; Tania del Rivero; Subhas Mukherjee; Sanjay Nag; Alexandros Gaitanidis; Dimitris Kadas; Christos Consoulas; Atanu Duttaroy; Subhabrata Sanyal
Journal:  Dev Cell       Date:  2011-10-18       Impact factor: 12.270

5.  Oxidative stress mediates tau-induced neurodegeneration in Drosophila.

Authors:  Dora Dias-Santagata; Tudor A Fulga; Atanu Duttaroy; Mel B Feany
Journal:  J Clin Invest       Date:  2006-12-14       Impact factor: 14.808

6.  In vitro metal uptake by recombinant human manganese superoxide dismutase.

Authors:  Mei M Whittaker; James W Whittaker
Journal:  Arch Biochem Biophys       Date:  2009-09-13       Impact factor: 4.013

7.  The interaction of mitochondrial iron with manganese superoxide dismutase.

Authors:  Amornrat Naranuntarat; Laran T Jensen; Samuel Pazicni; James E Penner-Hahn; Valeria C Culotta
Journal:  J Biol Chem       Date:  2009-06-27       Impact factor: 5.157

Review 8.  MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx.

Authors:  Demet Candas; Jian Jian Li
Journal:  Antioxid Redox Signal       Date:  2013-06-08       Impact factor: 8.401

9.  Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants.

Authors:  Nicole Piazza; Michael Hayes; Ian Martin; Atanu Duttaroy; Mike Grotewiel; Robert Wessells
Journal:  Biogerontology       Date:  2009-01-16       Impact factor: 4.277

10.  Mitochondrial manganese superoxide dismutase mRNA expression in human chorioamniotic membranes and its association with labor, inflammation, and infection.

Authors:  Nandor Gabor Than; Roberto Romero; Adi L Tarca; Sorin Draghici; Offer Erez; Tinnakorn Chaiworapongsa; Yeon Mee Kim; Sun Kwon Kim; Edi Vaisbuch; Gerard Tromp
Journal:  J Matern Fetal Neonatal Med       Date:  2009-11
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.