| Literature DB >> 14703697 |
Véronique Le Guern1, Geneviève Le Roux, Antoine Martin, Jean Feuillard, Pascal Cohen, Hélène Poirel, Martine Raphaël, Loïc Guillevin, Luc Mouthon.
Abstract
Common variable immunodeficiency (CVID) is a primary defect that is characterized by impaired antibody production. CVID patients may develop recurrent infections, autoimmune disorders and/or systemic granulomatosis. It is well documented that CVID patients are at risk to develop malignant lymphomas. However, to the best of our knowledge, lymphoma complicating the course of CVID associated with systemic granulomatosis has never been reported. We describe two CVID patients with systemic granulomatosis who developed B-cell lymphomas, one related to Epstein Barr virus infection, 5 and 12 yr after CVID had been diagnosed.Entities:
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Year: 2003 PMID： 14703697 DOI： 10.1046/j.0902-4441.2003.00082.x
Source DB: PubMed Journal: Eur J Haematol ISSN： 0902-4441 Impact factor: 2.997