Literature DB >> 14703063

The 870G>A polymorphism of the cyclin D1 gene is not associated with breast cancer.

Peter Krippl1, Uwe Langsenlehner, Wilfried Renner, Babak Yazdani-Biuki, Gerald Wolf, Thomas C Wascher, Bernhard Paulweber, Werner Weitzer, Andreas Leithner, Hellmut Samonigg.   

Abstract

A common 870G > A polymorphism in the gene for cyclin D1, CCND1, has been linked to alternative splicing and cancer susceptibility. To analyze its role for breast cancer, we determined the CCND1 genotype in 500 breast cancer patients and 500 controls. CCND1 genotype frequencies were similar among patients and controls. The CCND1 genotype was furthermore not associated with tumor characteristics. We conclude that the CCND1 870G > A polymorphism is not associated with breast cancer.

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Year:  2003        PMID: 14703063     DOI: 10.1023/B:BREA.0000004372.20461.33

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN: 0167-6806            Impact factor:   4.872


  11 in total

1.  Association of CCND1 Gene c.870G>A Polymorphism with Breast Cancer Risk: A Case-ControlStudy and a Meta-Analysis.

Authors:  Zahra Soleimani; Davood Kheirkhah; Mohammad Reza Sharif; Alireza Sharif; Mohammad Karimian; Younes Aftabi
Journal:  Pathol Oncol Res       Date:  2016-12-21       Impact factor: 3.201

2.  Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.

Authors:  Theodoros N Sergentanis; Konstantinos P Economopoulos
Journal:  Mol Biol Rep       Date:  2010-12-14       Impact factor: 2.316

3.  Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome.

Authors:  E K A Millar; J L Dean; C M McNeil; S A O'Toole; S M Henshall; T Tran; J Lin; A Quong; C E S Comstock; A Witkiewicz; E A Musgrove; H Rui; L Lemarchand; V W Setiawan; C A Haiman; K E Knudsen; R L Sutherland; E S Knudsen
Journal:  Oncogene       Date:  2009-03-16       Impact factor: 9.867

4.  Cyclin D1 G870A polymorphism and the risk of hepatocellular carcinoma in a Chinese population.

Authors:  Zhangyong Hu; Zhipeng Zhou; Guolian Xiong; Yali Wang; Yi Lai; Lan Deng; Jinliang Yang
Journal:  Tumour Biol       Date:  2014-02-26

5.  Association between CCND1 G/A870 polymorphism, allele-specific amplification, cyclin D1 expression, and survival in esophageal and lung carcinoma.

Authors:  Vanita K Gupta; Andrew Feber; Liqiang Xi; Arjun Pennathur; Maoxin Wu; James D Luketich; Tony E Godfrey
Journal:  Clin Cancer Res       Date:  2008-12-01       Impact factor: 12.531

6.  The cyclin D1 (CCND1) G870A polymorphism and lung cancer susceptibility: a meta-analysis.

Authors:  Changxi Zhou; Huaijie An; Mingdong Hu; Qinghui Liu; Peiliang Geng; Jiancheng Xu; Baojun Sun; Changting Liu
Journal:  Tumour Biol       Date:  2013-07-20

7.  Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer.

Authors:  Yuqing Li; Yi Li; Sara Wedrén; Guoliang Li; Tze Howe Charn; Kartiki Vasant Desai; Carine Bonnard; Kamila Czene; Keith Humphreys; Hatef Darabi; Kristjana Einarsdóttir; Tuomas Heikkinen; Kristiina Aittomäki; Carl Blomqvist; Kee Seng Chia; Heli Nevanlinna; Per Hall; Edison T Liu; Jianjun Liu
Journal:  Breast Cancer Res       Date:  2011-01-26       Impact factor: 6.466

8.  Genetic association between cyclin D1 polymorphism and breast cancer susceptibility.

Authors:  XiaoRui Li; XiaoQing Huo; WeiWei Li; QingHui Yang; Ying Wang; XiaoChun Kang
Journal:  Tumour Biol       Date:  2014-11-17

9.  Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk.

Authors:  Ummiye V Onay; Kirsimari Aaltonen; Laurent Briollais; Julia A Knight; Noel Pabalan; Outi Kilpivaara; Irene L Andrulis; Carl Blomqvist; Heli Nevanlinna; Hilmi Ozcelik
Journal:  BMC Cancer       Date:  2008-01-14       Impact factor: 4.430

10.  Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

Authors:  Christopher A Haiman; Rachel R Garcia; Chris Hsu; Lucy Xia; Helen Ha; Xin Sheng; Loic Le Marchand; Laurence N Kolonel; Brian E Henderson; Michael R Stallcup; Geoffrey L Greene; Michael F Press
Journal:  BMC Cancer       Date:  2009-01-30       Impact factor: 4.430

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