Literature DB >> 14702250

Social anxiety in outpatients with schizophrenia: a relevant cause of disability.

Stefano Pallanti1, Leonardo Quercioli, Eric Hollander.   

Abstract

OBJECTIVE: Social anxiety is a frequent but often unrecognized feature in schizophrenia and is associated with a severe level of disability. To precisely define the assessment, impact, clinical correlates, and consequences of social anxiety in schizophrenia, the authors conducted a survey of schizophrenia patients and a comparison cohort of patients with social anxiety disorder.
METHOD: A consecutively enrolled group of 80 outpatients with DSM-IV schizophrenia and a consecutive comparison group of 27 patients with social anxiety disorder were recruited from an institutional psychiatric practice and assessed with the Liebowitz Social Anxiety Scale, Scale for the Assessment of Negative Symptoms, Scale for the Assessment of Positive Symptoms, Social Adjustment Scale, and the Medical Outcomes Study 36-item Short-Form Health Survey.
RESULTS: Social anxiety scores of schizophrenia patients with comorbid social anxiety disorder (N=29, 36.3%) did not differ from those of subjects with social anxiety disorder as their primary diagnosis. Schizophrenia patients without social anxiety disorder had significantly lower total scores on the Liebowitz Social Anxiety Scale and lower social and performance anxiety subscale scores than did the other two groups. No differences in negative and positive symptom rates were found between schizophrenia patients with and without social anxiety disorder. Schizophrenia patients with social anxiety disorder had a higher lifetime rate of suicide attempts, greater lethality of suicide attempts, more past substance/alcohol abuse disorder, lower social adjustment, and lower overall quality of life.
CONCLUSIONS: Social anxiety is a highly prevalent, disabling condition in outpatients with schizophrenia that is unrelated to clinical psychotic symptoms. The Liebowitz Social Anxiety Scale appeared adequate and reliable in assessing social anxiety disorder in patients with schizophrenia. If these data are confirmed, this study will make a contribution to the search for operational guidelines and adequate next-step treatments for social anxiety disorder in schizophrenia patients.

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Mesh:

Year:  2004        PMID: 14702250     DOI: 10.1176/appi.ajp.161.1.53

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  41 in total

1.  Association of stigma, self-esteem, and symptoms with concurrent and prospective assessment of social anxiety in schizophrenia.

Authors:  Paul H Lysaker; Philip T Yanos; Jared Outcalt; David Roe
Journal:  Clin Schizophr Relat Psychoses       Date:  2010-04

2.  Co-morbid anxiety disorders in patients with schizophrenia in a tertiary institution in South East Nigeria: prevalence and correlates.

Authors:  Chinyere Aguocha; Kelechi Aguocha; Richard Uwakwe; Gabriel Onyeama
Journal:  Afr Health Sci       Date:  2015-03       Impact factor: 0.927

3.  The moderating effects of perceived intentionality: exploring the relationships between ideas of reference, paranoia and social anxiety in schizotypy.

Authors:  Sean C Morrison; Alex S Cohen
Journal:  Cogn Neuropsychiatry       Date:  2014-07-02       Impact factor: 1.871

4.  Sex-dependent behavioral effects and morphological changes in the hippocampus after prenatal invasive interventions in rats: implications for animal models of schizophrenia.

Authors:  Martina von Wilmsdorff; Ulrich Sprick; Marie-Luise Bouvier; Daniela Schulz; Andrea Schmitt; Wolfgang Gaebel
Journal:  Clinics (Sao Paulo)       Date:  2010-02       Impact factor: 2.365

5.  Social anxiety disorder in schizophrenia: a neglected, yet potentially important comorbidity.

Authors:  Marc-André Roy; Marie-France Demers; Amélie M Achim
Journal:  J Psychiatry Neurosci       Date:  2018-07       Impact factor: 6.186

6.  Childhood temperament is associated with distress, anxiety and reduced quality of life in schizophrenia spectrum disorders.

Authors:  Brandee Feola; Kristan Armstrong; Neil D Woodward; Stephan Heckers; Jennifer Urbano Blackford
Journal:  Psychiatry Res       Date:  2019-03-11       Impact factor: 3.222

Review 7.  How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association.

Authors:  Amélie M Achim; Michel Maziade; Eric Raymond; David Olivier; Chantal Mérette; Marc-André Roy
Journal:  Schizophr Bull       Date:  2009-12-03       Impact factor: 9.306

Review 8.  Anxiety as a core aspect of schizophrenia.

Authors:  Stefano Pallanti; Andrea Cantisani; Giacomo Grassi
Journal:  Curr Psychiatry Rep       Date:  2013-05       Impact factor: 5.285

9.  Emotional experience predicts social adjustment independent of neurocognition and social cognition in schizophrenia.

Authors:  Ivy F Tso; Tyler B Grove; Stephan F Taylor
Journal:  Schizophr Res       Date:  2010-01-03       Impact factor: 4.939

10.  Paranoid Thoughts in Adolescents with Social Anxiety Disorder.

Authors:  S Pisano; G Catone; A Pascotto; R Iuliano; C Tiano; A Milone; G Masi; A Gritti
Journal:  Child Psychiatry Hum Dev       Date:  2016-10
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