Smart nanotubes for biomedical and biotechnological applications.

Nanoparticles are being developed for a host of biomedical and biotechnological applications including drug delivery, enzyme immobilization and DNA transfection. Spherical nanoparticles are typically used for such applications, but this only reflects the fact that spheres are easier to make than other shapes. Micro- and nanotubes--structures that resemble tiny drinking straws--are alternatives and may offer advantages over spherical nanoparticles for some applications. This article discusses four different approaches to making micro- and nanotubes and reviews the current status of efforts to develop biomedical and biotechnological applications of these tubular structures.