Literature DB >> 14700200

Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities.

Vineet Kumar1, Ashok K Prasad, Virinder S Parmar.   

Abstract

Aristolactams, having a phenanthrene chromophore are a small group of compounds mainly found in the Aristolochiaceae together with the aristolochic acids and 4,5-dioxoaporphines. In this report, these three important classes of natural products are reviewed and classified on the basis of their oxygenation pattern. In addition the biological activities of these compounds and their general chemistry are discussed.

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Year:  2003        PMID： 14700200     DOI： 10.1039/b303648k

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  26 in total

1.  Aristolochic Acid in the Etiology of Renal Cell Carcinoma.

Authors:  Margaret L Hoang; Chung-Hsin Chen; Pau-Chung Chen; Nicholas J Roberts; Kathleen G Dickman; Byeong Hwa Yun; Robert J Turesky; Yeong-Shiau Pu; Bert Vogelstein; Nickolas Papadopoulos; Arthur P Grollman; Kenneth W Kinzler; Thomas A Rosenquist
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2016-08-23       Impact factor: 4.254

2.  Antineoplastic agents. 573. isolation and structure of papilistatin from the papilionid butterfly Byasa polyeuctes termessa.

Authors:  George R Pettit; Qinghua Ye; Delbert L Herald; Fiona Hogan; Robin K Pettit
Journal:  J Nat Prod       Date:  2010-02-26       Impact factor: 4.050

3.  Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.

Authors:  Keiji Hashimoto; Irina N Zaitseva; Radha Bonala; Sivaprasad Attaluri; Katherine Ozga; Charles R Iden; Francis Johnson; Masaaki Moriya; Arthur P Grollman; Viktoriya S Sidorenko
Journal:  Carcinogenesis       Date:  2016-04-18       Impact factor: 4.944

4.  Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.

Authors:  Margaret L Hoang; Chung-Hsin Chen; Viktoriya S Sidorenko; Jian He; Kathleen G Dickman; Byeong Hwa Yun; Masaaki Moriya; Noushin Niknafs; Christopher Douville; Rachel Karchin; Robert J Turesky; Yeong-Shiau Pu; Bert Vogelstein; Nickolas Papadopoulos; Arthur P Grollman; Kenneth W Kinzler; Thomas A Rosenquist
Journal:  Sci Transl Med       Date:  2013-08-07       Impact factor: 17.956

5.  The natural product Aristolactam AIIIa as a new ligand targeting the polo-box domain of polo-like kinase 1 potently inhibits cancer cell proliferation.

Authors:  Li Li; Xu Wang; Jing Chen; Hong Ding; Yu Zhang; Tian-Cen Hu; Li-Hong Hu; Hua-Liang Jiang; Xu Shen
Journal:  Acta Pharmacol Sin       Date:  2009-10       Impact factor: 6.150

6.  Identification of Aristolactam Derivatives That Act as Inhibitors of Human Immunodeficiency Virus Type 1 Infection and Replication by Targeting Tat-Mediated Viral Transcription.

Authors:  YoungHyun Shin; Chul Min Park; Hong Gi Kim; Dong-Eun Kim; Min Suk Choi; Jeong-Ah Kim; Byeong-Sun Choi; Cheol-Hee Yoon
Journal:  Virol Sin       Date:  2020-08-10       Impact factor: 4.327

7.  Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Authors:  Shinya Shibutani; Radha R Bonala; Thomas Rosenquist; Robert Rieger; Naomi Suzuki; Francis Johnson; Frederick Miller; Arthur P Grollman
Journal:  Int J Cancer       Date:  2010-09-01       Impact factor: 7.396

8.  Synthesis of 3-Alkylideneisoindolin-1-ones via Sonogashira Cyclocarbonylative Reactions of 2-Ethynylbenzamides.

Authors:  Gianluigi Albano; Stefano Giuntini; Laura Antonella Aronica
Journal:  J Org Chem       Date:  2020-07-14       Impact factor: 4.354

9.  Bioactivation of the human carcinogen aristolochic acid.

Authors:  Viktoriya S Sidorenko; Sivaprasad Attaluri; Irina Zaitseva; Charles R Iden; Kathleen G Dickman; Francis Johnson; Arthur P Grollman
Journal:  Carcinogenesis       Date:  2014-04-17       Impact factor: 4.944

10.  Characterization of the basal angiosperm Aristolochia fimbriata: a potential experimental system for genetic studies.

Authors:  Barbara J Bliss; Stefan Wanke; Abdelali Barakat; Saravanaraj Ayyampalayam; Norman Wickett; P Kerr Wall; Yuannian Jiao; Lena Landherr; Paula E Ralph; Yi Hu; Christoph Neinhuis; Jim Leebens-Mack; Kathiravetpilla Arumuganathan; Sandra W Clifton; Siela N Maximova; Hong Ma; Claude W dePamphilis
Journal:  BMC Plant Biol       Date:  2013-01-24       Impact factor: 4.215
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